STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRASV-Ha-ras Harvey rat sarcoma viral oncogene homolog. (189 aa)    
Predicted Functional Partners:
RASA1
RAS p21 protein activator (GTPase activating protein) 1.
   
 0.999
RALGDS
Ral guanine nucleotide dissociation stimulator.
   
 0.999
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.999
RAF1
RAF1 isoform 2; Belongs to the protein kinase superfamily.
   
 0.999
RASSF5
Ras association (RalGDS/AF-6) domain family member 5.
    
 0.997
BRAF
BRAF isoform 1; Belongs to the protein kinase superfamily.
   
 0.996
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
   
 0.995
AFDN
Afadin, adherens junction formation factor.
    
 0.995
ARAF
V-raf murine sarcoma 3611 viral oncogene homolog.
   
 0.989
RASGRP4
RAS guanyl releasing protein 4.
    
 0.988
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.