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STRINGSTRING
HBB protein (Pan troglodytes) - STRING interaction network
"HBB" - Hemoglobin subunit beta in Pan troglodytes
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues (147 aa)    
Predicted Functional Partners:
HP
Pan troglodytes haptoglobin-related protein (HPR), mRNA; Belongs to the peptidase S1 family (348 aa)
     
  0.923
HBZ
Hemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin (142 aa)
     
0.853
ENSPTRG00000007530
Uncharacterized protein; Belongs to the globin family (142 aa)
     
 
0.777
SCN2A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes (2005 aa)
           
  0.734
AHSP
Alpha hemoglobin stabilizing protein (102 aa)
     
 
  0.646
ACKR1
Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] (336 aa)
     
   
  0.636
HPR
Haptoglobin-related protein; Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron (384 aa)
     
 
  0.632
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein) (773 aa)
       
 
  0.554
DEFB1
Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (68 aa)
           
  0.539
KLF1
Kruppel-like factor 1 (erythroid) (362 aa)
     
 
  0.532
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, Pan troglodytes, chimpanzee
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