STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPP1Tripeptidyl-peptidase 1; Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity) (563 aa)    
Predicted Functional Partners:
MFSD8
Major facilitator superfamily domain containing 8; Uncharacterized protein
   
  
 0.805
CLN5
Uncharacterized protein; Ceroid-lipofuscinosis, neuronal 5
   
  
 0.783
CLN6
CLN6, transmembrane ER protein; Ceroid-lipofuscinosis, neuronal 6, late infantile, variant
      
 0.779
TINF2
Pan troglodytes TERF1 (TRF1)-interacting nuclear factor 2 (TINF2), mRNA
    
 
 0.750
TERF1
Telomeric repeat binding factor (NIMA-interacting) 1; Uncharacterized protein
      
 0.734
BTD
Uncharacterized protein; Biotinidase
      
 0.727
PPT1
Palmitoyl-protein thioesterase 1; Uncharacterized protein
   
  
 0.709
CLN8
Uncharacterized protein; Ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
   
  
 0.708
TERT
Uncharacterized protein; Telomerase reverse transcriptase
    
 
 0.652
POT1
Protection of telomeres 1 homolog; Uncharacterized protein
    
 
 0.622
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, Pan troglodytes, chimpanzee
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