OVCH2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OVCH2

OVCH2 isoform 1; Belongs to the peptidase S1 family. (564 aa)

Predicted Functional Partners:

OR52N5

0.808

OR52N1

0.784

CNTN5

0.715

SYT6

0.532

LILRA3

0.522

MST1R

0.511

MET

0.511

TRIP11

0.504

LOC104003639

0.477

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTN5	LILRA3	ENSPTRP00000007227	ENSPTRP00000080976	CNTN5 isoform 4.	LILRA1 isoform 5.	0.406
CNTN5	OR52N1	ENSPTRP00000007227	ENSPTRP00000005736	CNTN5 isoform 4.	Olfactory receptor family 52 subfamily N member 1; Belongs to the G-protein coupled receptor 1 family.	0.696
CNTN5	OR52N5	ENSPTRP00000007227	ENSPTRP00000090802	CNTN5 isoform 4.	LOW QUALITY PROTEIN: olfactory receptor 52N5.	0.704
CNTN5	OVCH2	ENSPTRP00000007227	ENSPTRP00000005801	CNTN5 isoform 4.	OVCH2 isoform 1; Belongs to the peptidase S1 family.	0.715
CNTN5	SYT6	ENSPTRP00000007227	ENSPTRP00000087479	CNTN5 isoform 4.	Synaptotagmin 6.	0.452
CNTN5	TRIP11	ENSPTRP00000007227	ENSPTRP00000011324	CNTN5 isoform 4.	TRIP11 isoform 1.	0.427
LILRA3	CNTN5	ENSPTRP00000080976	ENSPTRP00000007227	LILRA1 isoform 5.	CNTN5 isoform 4.	0.406
LILRA3	OR52N1	ENSPTRP00000080976	ENSPTRP00000005736	LILRA1 isoform 5.	Olfactory receptor family 52 subfamily N member 1; Belongs to the G-protein coupled receptor 1 family.	0.522
LILRA3	OR52N5	ENSPTRP00000080976	ENSPTRP00000090802	LILRA1 isoform 5.	LOW QUALITY PROTEIN: olfactory receptor 52N5.	0.522
LILRA3	OVCH2	ENSPTRP00000080976	ENSPTRP00000005801	LILRA1 isoform 5.	OVCH2 isoform 1; Belongs to the peptidase S1 family.	0.522
LOC104003639	MET	ENSPTRP00000063078	ENSPTRP00000083162	Guanine nucleotide-binding protein G(s) subunit alpha.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.644
LOC104003639	MST1R	ENSPTRP00000063078	ENSPTRP00000025788	Guanine nucleotide-binding protein G(s) subunit alpha.	Macrophage stimulating 1 receptor.	0.644
LOC104003639	OVCH2	ENSPTRP00000063078	ENSPTRP00000005801	Guanine nucleotide-binding protein G(s) subunit alpha.	OVCH2 isoform 1; Belongs to the peptidase S1 family.	0.477
MET	LOC104003639	ENSPTRP00000083162	ENSPTRP00000063078	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Guanine nucleotide-binding protein G(s) subunit alpha.	0.644
MET	MST1R	ENSPTRP00000083162	ENSPTRP00000025788	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Macrophage stimulating 1 receptor.	0.738
MET	OVCH2	ENSPTRP00000083162	ENSPTRP00000005801	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	OVCH2 isoform 1; Belongs to the peptidase S1 family.	0.511
MST1R	LOC104003639	ENSPTRP00000025788	ENSPTRP00000063078	Macrophage stimulating 1 receptor.	Guanine nucleotide-binding protein G(s) subunit alpha.	0.644
MST1R	MET	ENSPTRP00000025788	ENSPTRP00000083162	Macrophage stimulating 1 receptor.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.738
MST1R	OVCH2	ENSPTRP00000025788	ENSPTRP00000005801	Macrophage stimulating 1 receptor.	OVCH2 isoform 1; Belongs to the peptidase S1 family.	0.511
OR52N1	CNTN5	ENSPTRP00000005736	ENSPTRP00000007227	Olfactory receptor family 52 subfamily N member 1; Belongs to the G-protein coupled receptor 1 family.	CNTN5 isoform 4.	0.696