| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADCYAP1R1 | FSHB | ENSPTRP00000074328 | ENSPTRP00000006017 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.793 |
| ADORA2A | FSHB | ENSPTRP00000024404 | ENSPTRP00000006017 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.752 |
| AMH | FSHB | ENSPTRP00000017388 | ENSPTRP00000006017 | Anti-Mullerian hormone. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.727 |
| AMH | FSHR | ENSPTRP00000017388 | ENSPTRP00000020457 | Anti-Mullerian hormone. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.814 |
| AMH | LHCGR | ENSPTRP00000017388 | ENSPTRP00000020451 | Anti-Mullerian hormone. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.798 |
| AMH | PRL | ENSPTRP00000017388 | ENSPTRP00000030340 | Anti-Mullerian hormone. | PRL isoform 1. | 0.646 |
| AMH | TSHR | ENSPTRP00000017388 | ENSPTRP00000091100 | Anti-Mullerian hormone. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.503 |
| CGA | FSHB | ENSPTRP00000088679 | ENSPTRP00000006017 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.998 |
| CGA | FSHR | ENSPTRP00000088679 | ENSPTRP00000020457 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.809 |
| CGA | GNRHR | ENSPTRP00000088679 | ENSPTRP00000027689 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Gonadotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. | 0.506 |
| CGA | LHCGR | ENSPTRP00000088679 | ENSPTRP00000020451 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.726 |
| CGA | PRL | ENSPTRP00000088679 | ENSPTRP00000030340 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | PRL isoform 1. | 0.576 |
| CGA | TSHR | ENSPTRP00000088679 | ENSPTRP00000091100 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.808 |
| CRHR1 | FSHB | ENSPTRP00000064542 | ENSPTRP00000006017 | Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.714 |
| FSHB | ADCYAP1R1 | ENSPTRP00000006017 | ENSPTRP00000074328 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. | 0.793 |
| FSHB | ADORA2A | ENSPTRP00000006017 | ENSPTRP00000024404 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | 0.752 |
| FSHB | AMH | ENSPTRP00000006017 | ENSPTRP00000017388 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Anti-Mullerian hormone. | 0.727 |
| FSHB | CGA | ENSPTRP00000006017 | ENSPTRP00000088679 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.998 |
| FSHB | CRHR1 | ENSPTRP00000006017 | ENSPTRP00000064542 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.714 |
| FSHB | FSHR | ENSPTRP00000006017 | ENSPTRP00000020457 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.998 |
