ATG13 protein (Pan troglodytes) - STRING interaction network

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ATG13

Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. (550 aa)

Predicted Functional Partners:

ATG101

0.999

RB1CC1

0.999

ENSPTRP00000089676

0.999

ULK2

0.986

ATG14

0.930

PIK3C3

0.919

MAP1LC3A

0.907

GABARAP

0.899

RPTOR

0.871

PIK3R4

0.866

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG101	ATG13	ENSPTRP00000008480	ENSPTRP00000079168	Chromosome 12 open reading frame 44.	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	0.999
ATG101	ATG14	ENSPTRP00000008480	ENSPTRP00000010813	Chromosome 12 open reading frame 44.	ATG14 autophagy related 14 homolog.	0.988
ATG101	ENSPTRP00000089676	ENSPTRP00000008480	ENSPTRP00000089676	Chromosome 12 open reading frame 44.	annotation not available	0.997
ATG101	GABARAP	ENSPTRP00000008480	ENSPTRP00000014784	Chromosome 12 open reading frame 44.	GABA type A receptor-associated protein.	0.630
ATG101	MAP1LC3A	ENSPTRP00000008480	ENSPTRP00000023008	Chromosome 12 open reading frame 44.	Microtubule associated protein 1 light chain 3 alpha.	0.508
ATG101	PIK3C3	ENSPTRP00000008480	ENSPTRP00000091735	Chromosome 12 open reading frame 44.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.987
ATG101	PIK3R4	ENSPTRP00000008480	ENSPTRP00000026520	Chromosome 12 open reading frame 44.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.985
ATG101	RB1CC1	ENSPTRP00000008480	ENSPTRP00000034671	Chromosome 12 open reading frame 44.	RB1-inducible coiled-coil 1.	0.999
ATG101	RPTOR	ENSPTRP00000008480	ENSPTRP00000016590	Chromosome 12 open reading frame 44.	Regulatory associated protein of MTOR, complex 1.	0.981
ATG101	ULK2	ENSPTRP00000008480	ENSPTRP00000092410	Chromosome 12 open reading frame 44.	Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.	0.997
ATG13	ATG101	ENSPTRP00000079168	ENSPTRP00000008480	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	Chromosome 12 open reading frame 44.	0.999
ATG13	ATG14	ENSPTRP00000079168	ENSPTRP00000010813	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	ATG14 autophagy related 14 homolog.	0.930
ATG13	ENSPTRP00000089676	ENSPTRP00000079168	ENSPTRP00000089676	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	annotation not available	0.999
ATG13	GABARAP	ENSPTRP00000079168	ENSPTRP00000014784	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	GABA type A receptor-associated protein.	0.899
ATG13	MAP1LC3A	ENSPTRP00000079168	ENSPTRP00000023008	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	Microtubule associated protein 1 light chain 3 alpha.	0.907
ATG13	PIK3C3	ENSPTRP00000079168	ENSPTRP00000091735	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.919
ATG13	PIK3R4	ENSPTRP00000079168	ENSPTRP00000026520	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.866
ATG13	RB1CC1	ENSPTRP00000079168	ENSPTRP00000034671	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	RB1-inducible coiled-coil 1.	0.999
ATG13	RPTOR	ENSPTRP00000079168	ENSPTRP00000016590	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	Regulatory associated protein of MTOR, complex 1.	0.871
ATG13	ULK2	ENSPTRP00000079168	ENSPTRP00000092410	Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.	Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.	0.986

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