| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COP1 | COPS2 | ENSPTRP00000051495 | ENSPTRP00000012052 | Ring finger and WD repeat domain 2. | COP9 constitutive photomorphogenic homolog subunit 2. | 0.601 |
| COP1 | CUL4B | ENSPTRP00000051495 | ENSPTRP00000038292 | Ring finger and WD repeat domain 2. | CUL4B isoform 3; Belongs to the cullin family. | 0.928 |
| COP1 | DDB1 | ENSPTRP00000051495 | ENSPTRP00000081878 | Ring finger and WD repeat domain 2. | Damage-specific DNA binding protein 1, 127kDa. | 0.980 |
| COP1 | DDB2 | ENSPTRP00000051495 | ENSPTRP00000006178 | Ring finger and WD repeat domain 2. | Damage-specific DNA binding protein 2, 48kDa. | 0.978 |
| COP1 | ERCC8 | ENSPTRP00000051495 | ENSPTRP00000028950 | Ring finger and WD repeat domain 2. | Excision repair cross-complementing rodent repair deficiency, complementation group 8. | 0.950 |
| COP1 | RBX1 | ENSPTRP00000051495 | ENSPTRP00000024839 | Ring finger and WD repeat domain 2. | Ring-box 1, E3 ubiquitin protein ligase. | 0.950 |
| COP1 | TP53 | ENSPTRP00000051495 | ENSPTRP00000014836 | Ring finger and WD repeat domain 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.985 |
| COPS2 | COP1 | ENSPTRP00000012052 | ENSPTRP00000051495 | COP9 constitutive photomorphogenic homolog subunit 2. | Ring finger and WD repeat domain 2. | 0.601 |
| COPS2 | COPS3 | ENSPTRP00000012052 | ENSPTRP00000015053 | COP9 constitutive photomorphogenic homolog subunit 2. | COP9 constitutive photomorphogenic homolog subunit 3. | 0.999 |
| COPS2 | CUL4B | ENSPTRP00000012052 | ENSPTRP00000038292 | COP9 constitutive photomorphogenic homolog subunit 2. | CUL4B isoform 3; Belongs to the cullin family. | 0.974 |
| COPS2 | DDB1 | ENSPTRP00000012052 | ENSPTRP00000081878 | COP9 constitutive photomorphogenic homolog subunit 2. | Damage-specific DNA binding protein 1, 127kDa. | 0.962 |
| COPS2 | DDB2 | ENSPTRP00000012052 | ENSPTRP00000006178 | COP9 constitutive photomorphogenic homolog subunit 2. | Damage-specific DNA binding protein 2, 48kDa. | 0.989 |
| COPS2 | ERCC8 | ENSPTRP00000012052 | ENSPTRP00000028950 | COP9 constitutive photomorphogenic homolog subunit 2. | Excision repair cross-complementing rodent repair deficiency, complementation group 8. | 0.937 |
| COPS2 | RBX1 | ENSPTRP00000012052 | ENSPTRP00000024839 | COP9 constitutive photomorphogenic homolog subunit 2. | Ring-box 1, E3 ubiquitin protein ligase. | 0.953 |
| COPS2 | XPC | ENSPTRP00000012052 | ENSPTRP00000051558 | COP9 constitutive photomorphogenic homolog subunit 2. | XPC complex subunit, DNA damage recognition and repair factor. | 0.649 |
| COPS3 | COPS2 | ENSPTRP00000015053 | ENSPTRP00000012052 | COP9 constitutive photomorphogenic homolog subunit 3. | COP9 constitutive photomorphogenic homolog subunit 2. | 0.999 |
| COPS3 | CUL4B | ENSPTRP00000015053 | ENSPTRP00000038292 | COP9 constitutive photomorphogenic homolog subunit 3. | CUL4B isoform 3; Belongs to the cullin family. | 0.958 |
| COPS3 | DDB1 | ENSPTRP00000015053 | ENSPTRP00000081878 | COP9 constitutive photomorphogenic homolog subunit 3. | Damage-specific DNA binding protein 1, 127kDa. | 0.970 |
| COPS3 | DDB2 | ENSPTRP00000015053 | ENSPTRP00000006178 | COP9 constitutive photomorphogenic homolog subunit 3. | Damage-specific DNA binding protein 2, 48kDa. | 0.980 |
| COPS3 | ERCC8 | ENSPTRP00000015053 | ENSPTRP00000028950 | COP9 constitutive photomorphogenic homolog subunit 3. | Excision repair cross-complementing rodent repair deficiency, complementation group 8. | 0.920 |
