CD6 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALCAM	CD4	ENSPTRP00000073368	ENSPTRP00000054833	Activated leukocyte cell adhesion molecule.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.439
ALCAM	CD6	ENSPTRP00000073368	ENSPTRP00000092309	Activated leukocyte cell adhesion molecule.	CD6 isoform 1.	0.998
CD2	CD247	ENSPTRP00000051908	ENSPTRP00000044167	CD2 isoform 1.	CD247 isoform 2.	0.918
CD2	CD3D	ENSPTRP00000051908	ENSPTRP00000007442	CD2 isoform 1.	CD3D isoform 1.	0.920
CD2	CD3E	ENSPTRP00000051908	ENSPTRP00000007441	CD2 isoform 1.	CD3E isoform 2.	0.944
CD2	CD3G	ENSPTRP00000051908	ENSPTRP00000007443	CD2 isoform 1.	CD3G isoform 1.	0.907
CD2	CD4	ENSPTRP00000051908	ENSPTRP00000054833	CD2 isoform 1.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.844
CD2	CD5	ENSPTRP00000051908	ENSPTRP00000048059	CD2 isoform 1.	CD5 isoform 1.	0.879
CD2	CD6	ENSPTRP00000051908	ENSPTRP00000092309	CD2 isoform 1.	CD6 isoform 1.	0.819
CD2	ITK	ENSPTRP00000051908	ENSPTRP00000029829	CD2 isoform 1.	Tyrosine-protein kinase.	0.895
CD247	CD2	ENSPTRP00000044167	ENSPTRP00000051908	CD247 isoform 2.	CD2 isoform 1.	0.918
CD247	CD3D	ENSPTRP00000044167	ENSPTRP00000007442	CD247 isoform 2.	CD3D isoform 1.	0.999
CD247	CD3E	ENSPTRP00000044167	ENSPTRP00000007441	CD247 isoform 2.	CD3E isoform 2.	0.999
CD247	CD3G	ENSPTRP00000044167	ENSPTRP00000007443	CD247 isoform 2.	CD3G isoform 1.	0.999
CD247	CD4	ENSPTRP00000044167	ENSPTRP00000054833	CD247 isoform 2.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.712
CD247	CD5	ENSPTRP00000044167	ENSPTRP00000048059	CD247 isoform 2.	CD5 isoform 1.	0.526
CD247	CD6	ENSPTRP00000044167	ENSPTRP00000092309	CD247 isoform 2.	CD6 isoform 1.	0.903
CD247	ITK	ENSPTRP00000044167	ENSPTRP00000029829	CD247 isoform 2.	Tyrosine-protein kinase.	0.949
CD3D	CD2	ENSPTRP00000007442	ENSPTRP00000051908	CD3D isoform 1.	CD2 isoform 1.	0.920
CD3D	CD247	ENSPTRP00000007442	ENSPTRP00000044167	CD3D isoform 1.	CD247 isoform 2.	0.999