ESRRA protein (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

ESRRA

Estrogen-related receptor alpha. (422 aa)

Predicted Functional Partners:

PPARGC1A

0.999

PPARGC1B

0.981

ESRRG

0.880

NRIP1

0.771

NCOR1

0.721

PPARG

0.703

ESR1

0.698

ATP5F1B

0.692

SLC7A1

0.665

RUNX2

0.662

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP5F1B	ESRRA	ENSPTRP00000008686	ENSPTRP00000006596	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Estrogen-related receptor alpha.	0.692
ATP5F1B	PPARGC1B	ENSPTRP00000008686	ENSPTRP00000077450	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	PPARGC1B isoform 2.	0.678
ESR1	ESRRA	ENSPTRP00000031932	ENSPTRP00000006596	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen-related receptor alpha.	0.698
ESR1	ESRRG	ENSPTRP00000031932	ENSPTRP00000085369	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen related receptor gamma.	0.464
ESR1	NCOR1	ENSPTRP00000031932	ENSPTRP00000075557	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor corepressor 1.	0.996
ESR1	NRIP1	ENSPTRP00000031932	ENSPTRP00000080348	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor interacting protein 1.	0.981
ESR1	PPARG	ENSPTRP00000031932	ENSPTRP00000076701	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Peroxisome proliferator-activated receptor gamma isoform X2.	0.645
ESR1	PPARGC1A	ENSPTRP00000031932	ENSPTRP00000027470	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	PPARG coactivator 1 alpha.	0.855
ESR1	PPARGC1B	ENSPTRP00000031932	ENSPTRP00000077450	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	PPARGC1B isoform 2.	0.753
ESR1	RUNX2	ENSPTRP00000031932	ENSPTRP00000065999	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.842
ESR1	SLC7A1	ENSPTRP00000031932	ENSPTRP00000009787	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 1.	0.470
ESRRA	ATP5F1B	ENSPTRP00000006596	ENSPTRP00000008686	Estrogen-related receptor alpha.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.692
ESRRA	ESR1	ENSPTRP00000006596	ENSPTRP00000031932	Estrogen-related receptor alpha.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.698
ESRRA	ESRRG	ENSPTRP00000006596	ENSPTRP00000085369	Estrogen-related receptor alpha.	Estrogen related receptor gamma.	0.880
ESRRA	NCOR1	ENSPTRP00000006596	ENSPTRP00000075557	Estrogen-related receptor alpha.	Nuclear receptor corepressor 1.	0.721
ESRRA	NRIP1	ENSPTRP00000006596	ENSPTRP00000080348	Estrogen-related receptor alpha.	Nuclear receptor interacting protein 1.	0.771
ESRRA	PPARG	ENSPTRP00000006596	ENSPTRP00000076701	Estrogen-related receptor alpha.	Peroxisome proliferator-activated receptor gamma isoform X2.	0.703
ESRRA	PPARGC1A	ENSPTRP00000006596	ENSPTRP00000027470	Estrogen-related receptor alpha.	PPARG coactivator 1 alpha.	0.999
ESRRA	PPARGC1B	ENSPTRP00000006596	ENSPTRP00000077450	Estrogen-related receptor alpha.	PPARGC1B isoform 2.	0.981
ESRRA	RUNX2	ENSPTRP00000006596	ENSPTRP00000065999	Estrogen-related receptor alpha.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.662