| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BLM | EME1 | ENSPTRP00000012754 | ENSPTRP00000015960 | BLM isoform 1. | Essential meiotic structure-specific endonuclease 1. | 0.811 |
| BLM | EME2 | ENSPTRP00000012754 | ENSPTRP00000061043 | BLM isoform 1. | Essential meiotic structure-specific endonuclease subunit 2. | 0.684 |
| BLM | ERCC1 | ENSPTRP00000012754 | ENSPTRP00000076815 | BLM isoform 1. | ERCC excision repair 1, endonuclease non-catalytic subunit. | 0.634 |
| BLM | ERCC4 | ENSPTRP00000012754 | ENSPTRP00000053757 | BLM isoform 1. | Excision repair cross-complementing rodent repair deficiency, complementation group 4. | 0.893 |
| BLM | FANCM | ENSPTRP00000012754 | ENSPTRP00000010694 | BLM isoform 1. | Fanconi anemia, complementation group M. | 0.996 |
| BLM | MUS81 | ENSPTRP00000012754 | ENSPTRP00000006717 | BLM isoform 1. | MUS81 structure-specific endonuclease subunit. | 0.945 |
| BLM | RAD51 | ENSPTRP00000012754 | ENSPTRP00000068995 | BLM isoform 1. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.989 |
| BLM | SLX1A | ENSPTRP00000012754 | ENSPTRP00000058845 | BLM isoform 1. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.931 |
| BLM | SLX4 | ENSPTRP00000012754 | ENSPTRP00000013163 | BLM isoform 1. | SLX4 structure-specific endonuclease subunit. | 0.670 |
| BLM | WRN | ENSPTRP00000012754 | ENSPTRP00000091996 | BLM isoform 1. | WRN RecQ like helicase. | 0.608 |
| EME1 | BLM | ENSPTRP00000015960 | ENSPTRP00000012754 | Essential meiotic structure-specific endonuclease 1. | BLM isoform 1. | 0.811 |
| EME1 | EME2 | ENSPTRP00000015960 | ENSPTRP00000061043 | Essential meiotic structure-specific endonuclease 1. | Essential meiotic structure-specific endonuclease subunit 2. | 0.947 |
| EME1 | ERCC1 | ENSPTRP00000015960 | ENSPTRP00000076815 | Essential meiotic structure-specific endonuclease 1. | ERCC excision repair 1, endonuclease non-catalytic subunit. | 0.903 |
| EME1 | ERCC4 | ENSPTRP00000015960 | ENSPTRP00000053757 | Essential meiotic structure-specific endonuclease 1. | Excision repair cross-complementing rodent repair deficiency, complementation group 4. | 0.884 |
| EME1 | FANCM | ENSPTRP00000015960 | ENSPTRP00000010694 | Essential meiotic structure-specific endonuclease 1. | Fanconi anemia, complementation group M. | 0.868 |
| EME1 | MUS81 | ENSPTRP00000015960 | ENSPTRP00000006717 | Essential meiotic structure-specific endonuclease 1. | MUS81 structure-specific endonuclease subunit. | 0.999 |
| EME1 | RAD51 | ENSPTRP00000015960 | ENSPTRP00000068995 | Essential meiotic structure-specific endonuclease 1. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.875 |
| EME1 | SLX1A | ENSPTRP00000015960 | ENSPTRP00000058845 | Essential meiotic structure-specific endonuclease 1. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.965 |
| EME1 | SLX4 | ENSPTRP00000015960 | ENSPTRP00000013163 | Essential meiotic structure-specific endonuclease 1. | SLX4 structure-specific endonuclease subunit. | 0.993 |
| EME1 | WRN | ENSPTRP00000015960 | ENSPTRP00000091996 | Essential meiotic structure-specific endonuclease 1. | WRN RecQ like helicase. | 0.788 |
