STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBM4BRBM4B isoform 1. (359 aa)    
Predicted Functional Partners:
EIF2A
Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
   
    0.561
GLI4
GLI family zinc finger 4.
    
 
 0.527
RNF44
RNF44 isoform 2.
   
 
 0.523
LIMCH1
LIM and calponin homology domains 1.
      
 0.522
LRRC23
Leucine rich repeat containing 23.
      
 0.522
PHRF1
PHRF1 isoform 1.
   
  
 0.513
TCF25
Transcription factor 25 (Basic helix-loop-helix).
    
 
 0.500
KCNA3
KCNA3 isoform 1; Belongs to the potassium channel family.
      
 0.485
DLGAP4
DLGAP4 isoform 4.
   
  
 0.479
SETD1A
SET domain containing 1A, histone lysine methyltransferase.
   
 
 0.477
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.