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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD42Ankyrin repeat domain 42. (527 aa)    
Predicted Functional Partners:
SFRP5
Secreted frizzled related protein 5.
    
 0.690
IQUB
IQUB isoform 2.
   
 
 0.654
DNAAF1
Dynein assembly factor 1, axonemal.
   
  0.645
SFRP2
Secreted frizzled-related protein 2.
    
 0.627
SFRP1
Secreted frizzled-related protein 1.
    
 0.580
FRZB
Frizzled-related protein.
    
 0.539
ACBD3
Acyl-CoA binding domain containing 3.
    
 0.442
POTEA
POTEA isoform 1.
  
 
  0.436
NOB1
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
   
 
 0.431
SGTB
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta.
   
 0.430
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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