| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CALHM1 | PANX1 | ENSPTRP00000005130 | ENSPTRP00000007193 | Calcium homeostasis modulator 1. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.656 |
| CALHM1 | PANX2 | ENSPTRP00000005130 | ENSPTRP00000057594 | Calcium homeostasis modulator 1. | Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. | 0.556 |
| CASP3 | CASP7 | ENSPTRP00000054330 | ENSPTRP00000074501 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | CASP7 isoform 1; Belongs to the peptidase C14A family. | 0.973 |
| CASP3 | PANX1 | ENSPTRP00000054330 | ENSPTRP00000007193 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.732 |
| CASP7 | CASP3 | ENSPTRP00000074501 | ENSPTRP00000054330 | CASP7 isoform 1; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.973 |
| CASP7 | PANX1 | ENSPTRP00000074501 | ENSPTRP00000007193 | CASP7 isoform 1; Belongs to the peptidase C14A family. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.754 |
| CK820_G0015936 | P2RX1 | ENSPTRP00000056913 | ENSPTRP00000014652 | C12orf76 isoform 1. | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. | 0.471 |
| CK820_G0015936 | PANX1 | ENSPTRP00000056913 | ENSPTRP00000007193 | C12orf76 isoform 1. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.805 |
| GRPR | PANX1 | ENSPTRP00000037174 | ENSPTRP00000007193 | Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.660 |
| KCNS1 | PANX1 | ENSPTRP00000023246 | ENSPTRP00000007193 | Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.604 |
| P2RX1 | CK820_G0015936 | ENSPTRP00000014652 | ENSPTRP00000056913 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. | C12orf76 isoform 1. | 0.471 |
| P2RX1 | PANX1 | ENSPTRP00000014652 | ENSPTRP00000007193 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.612 |
| P2RX4 | PANX1 | ENSPTRP00000009426 | ENSPTRP00000007193 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.717 |
| P2RX7 | PANX1 | ENSPTRP00000049853 | ENSPTRP00000007193 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. | Pannexin; Structural component of the gap junctions and the hemichannels. | 0.919 |
| PANX1 | CALHM1 | ENSPTRP00000007193 | ENSPTRP00000005130 | Pannexin; Structural component of the gap junctions and the hemichannels. | Calcium homeostasis modulator 1. | 0.656 |
| PANX1 | CASP3 | ENSPTRP00000007193 | ENSPTRP00000054330 | Pannexin; Structural component of the gap junctions and the hemichannels. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.732 |
| PANX1 | CASP7 | ENSPTRP00000007193 | ENSPTRP00000074501 | Pannexin; Structural component of the gap junctions and the hemichannels. | CASP7 isoform 1; Belongs to the peptidase C14A family. | 0.754 |
| PANX1 | CK820_G0015936 | ENSPTRP00000007193 | ENSPTRP00000056913 | Pannexin; Structural component of the gap junctions and the hemichannels. | C12orf76 isoform 1. | 0.805 |
| PANX1 | GRPR | ENSPTRP00000007193 | ENSPTRP00000037174 | Pannexin; Structural component of the gap junctions and the hemichannels. | Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. | 0.660 |
| PANX1 | KCNS1 | ENSPTRP00000007193 | ENSPTRP00000023246 | Pannexin; Structural component of the gap junctions and the hemichannels. | Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily. | 0.604 |
