BIRC3 protein (Pan troglodytes) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

BIRC3

Baculoviral IAP repeat containing 3. (610 aa)

Predicted Functional Partners:

TNFRSF1A

0.999

RIPK1

0.998

TRAF1

0.998

TRAF2

0.998

TRAF3

0.997

DIABLO

0.993

CASP9

0.993

TRADD

0.992

TRAF5

0.988

CASP3

0.988

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC3	CASP3	ENSPTRP00000090891	ENSPTRP00000054330	Baculoviral IAP repeat containing 3.	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	0.988
BIRC3	CASP9	ENSPTRP00000090891	ENSPTRP00000089496	Baculoviral IAP repeat containing 3.	CASP9 isoform 4; Belongs to the peptidase C14A family.	0.993
BIRC3	DIABLO	ENSPTRP00000090891	ENSPTRP00000071257	Baculoviral IAP repeat containing 3.	Diablo, IAP-binding mitochondrial protein.	0.993
BIRC3	RIPK1	ENSPTRP00000090891	ENSPTRP00000030180	Baculoviral IAP repeat containing 3.	Receptor (TNFRSF)-interacting serine-threonine kinase 1.	0.998
BIRC3	TNFRSF1A	ENSPTRP00000090891	ENSPTRP00000066030	Baculoviral IAP repeat containing 3.	Tumor necrosis factor receptor superfamily, member 1A.	0.999
BIRC3	TRADD	ENSPTRP00000090891	ENSPTRP00000046129	Baculoviral IAP repeat containing 3.	TNFRSF1A-associated via death domain.	0.992
BIRC3	TRAF1	ENSPTRP00000090891	ENSPTRP00000036416	Baculoviral IAP repeat containing 3.	TNF receptor-associated factor.	0.998
BIRC3	TRAF2	ENSPTRP00000090891	ENSPTRP00000036949	Baculoviral IAP repeat containing 3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.998
BIRC3	TRAF3	ENSPTRP00000090891	ENSPTRP00000011503	Baculoviral IAP repeat containing 3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.997
BIRC3	TRAF5	ENSPTRP00000090891	ENSPTRP00000003288	Baculoviral IAP repeat containing 3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.988
CASP3	BIRC3	ENSPTRP00000054330	ENSPTRP00000090891	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	Baculoviral IAP repeat containing 3.	0.988
CASP3	CASP9	ENSPTRP00000054330	ENSPTRP00000089496	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	CASP9 isoform 4; Belongs to the peptidase C14A family.	0.996
CASP3	DIABLO	ENSPTRP00000054330	ENSPTRP00000071257	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	Diablo, IAP-binding mitochondrial protein.	0.796
CASP3	RIPK1	ENSPTRP00000054330	ENSPTRP00000030180	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	Receptor (TNFRSF)-interacting serine-threonine kinase 1.	0.785
CASP3	TNFRSF1A	ENSPTRP00000054330	ENSPTRP00000066030	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	Tumor necrosis factor receptor superfamily, member 1A.	0.688
CASP3	TRADD	ENSPTRP00000054330	ENSPTRP00000046129	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	TNFRSF1A-associated via death domain.	0.670
CASP3	TRAF1	ENSPTRP00000054330	ENSPTRP00000036416	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	TNF receptor-associated factor.	0.497
CASP3	TRAF2	ENSPTRP00000054330	ENSPTRP00000036949	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.498
CASP3	TRAF3	ENSPTRP00000054330	ENSPTRP00000011503	Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.513
CASP9	BIRC3	ENSPTRP00000089496	ENSPTRP00000090891	CASP9 isoform 4; Belongs to the peptidase C14A family.	Baculoviral IAP repeat containing 3.	0.993