| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACAA2 | ACACA | ENSPTRP00000017023 | ENSPTRP00000074254 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA carboxylase alpha. | 0.426 |
| ACAA2 | ACADM | ENSPTRP00000017023 | ENSPTRP00000052172 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | 0.981 |
| ACAA2 | ACAT1 | ENSPTRP00000017023 | ENSPTRP00000007309 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.967 |
| ACAA2 | ACSS1 | ENSPTRP00000017023 | ENSPTRP00000022860 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-coenzyme A synthetase. | 0.898 |
| ACAA2 | EHHADH | ENSPTRP00000017023 | ENSPTRP00000027013 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.984 |
| ACAA2 | HADH | ENSPTRP00000017023 | ENSPTRP00000062385 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-CoA dehydrogenase. | 0.987 |
| ACAA2 | HADHA | ENSPTRP00000017023 | ENSPTRP00000020159 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.985 |
| ACAA2 | HMGCS1 | ENSPTRP00000017023 | ENSPTRP00000028865 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.981 |
| ACAA2 | HMGCS2 | ENSPTRP00000017023 | ENSPTRP00000002014 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.982 |
| ACAA2 | OXCT1 | ENSPTRP00000017023 | ENSPTRP00000084492 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.692 |
| ACACA | ACAA2 | ENSPTRP00000074254 | ENSPTRP00000017023 | Acetyl-CoA carboxylase alpha. | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.426 |
| ACACA | ACADM | ENSPTRP00000074254 | ENSPTRP00000052172 | Acetyl-CoA carboxylase alpha. | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | 0.464 |
| ACACA | ACAT1 | ENSPTRP00000074254 | ENSPTRP00000007309 | Acetyl-CoA carboxylase alpha. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.962 |
| ACACA | ACSS1 | ENSPTRP00000074254 | ENSPTRP00000022860 | Acetyl-CoA carboxylase alpha. | Acetyl-coenzyme A synthetase. | 0.936 |
| ACACA | EHHADH | ENSPTRP00000074254 | ENSPTRP00000027013 | Acetyl-CoA carboxylase alpha. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.711 |
| ACACA | HADHA | ENSPTRP00000074254 | ENSPTRP00000020159 | Acetyl-CoA carboxylase alpha. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.602 |
| ACADM | ACAA2 | ENSPTRP00000052172 | ENSPTRP00000017023 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.981 |
| ACADM | ACACA | ENSPTRP00000052172 | ENSPTRP00000074254 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Acetyl-CoA carboxylase alpha. | 0.464 |
| ACADM | ACAT1 | ENSPTRP00000052172 | ENSPTRP00000007309 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.971 |
| ACADM | ACSS1 | ENSPTRP00000052172 | ENSPTRP00000022860 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). | Acetyl-coenzyme A synthetase. | 0.444 |
