STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HYOU1Hypoxia up-regulated 1. (999 aa)    
Predicted Functional Partners:
HSPA5
Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.
  
0.988
LOC100609513
78 kDa glucose-regulated protein pseudogene.
   
0.984
SIL1
SIL1 nucleotide exchange factor.
   
 0.977
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.925
ANKRD45
Ankyrin repeat domain 45.
   
 
 0.917
ENSPTRP00000089993
annotation not available
   
 0.898
PDIA4
Protein disulfide-isomerase A4.
   
 0.897
PDIA4-2
Protein disulfide isomerase family A member 4.
   
 0.897
CALR
Calreticulin.
   
 0.895
DNAJC10
DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
  
 0.892
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.