STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNJ6KCNJ6 isoform 1. (323 aa)    
Predicted Functional Partners:
KCNJ3
Potassium voltage-gated channel subfamily J member 3.
  
0.989
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2.
   
 0.964
GABBR1
Gamma-aminobutyric acid type B receptor subunit 1.
   
 0.953
GNAO1
G protein subunit alpha o1.
   
 
 0.938
PRKACG
Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.
   
 
 0.921
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
   
 
 0.921
PRKACA
PRKACA isoform 7; Belongs to the protein kinase superfamily.
   
 
 0.920
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.910
GNAI3
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
   
 
 0.905
GNAI2
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.
   
 
 0.905
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.