Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCL2 | CDKN1A | ENSPTRP00000090293 | ENSPTRP00000060292 | BCL2 apoptosis regulator. | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | 0.655 |
| BCL2 | TP53 | ENSPTRP00000090293 | ENSPTRP00000014836 | BCL2 apoptosis regulator. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.998 |
| BCL2 | TP53AIP1 | ENSPTRP00000090293 | ENSPTRP00000007645 | BCL2 apoptosis regulator. | Tumor protein p53 regulated apoptosis inducing protein 1. | 0.491 |
| CDKN1A | BCL2 | ENSPTRP00000060292 | ENSPTRP00000090293 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | BCL2 apoptosis regulator. | 0.655 |
| CDKN1A | TP53 | ENSPTRP00000060292 | ENSPTRP00000014836 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.998 |
| CDKN1A | TP53AIP1 | ENSPTRP00000060292 | ENSPTRP00000007645 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | Tumor protein p53 regulated apoptosis inducing protein 1. | 0.422 |
| CDKN1A | TP63 | ENSPTRP00000060292 | ENSPTRP00000027067 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.451 |
| CDKN1A | TP73 | ENSPTRP00000060292 | ENSPTRP00000064772 | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. | 0.636 |
| DYRK2 | TP53 | ENSPTRP00000065905 | ENSPTRP00000014836 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.767 |
| DYRK2 | TP53AIP1 | ENSPTRP00000065905 | ENSPTRP00000007645 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. | Tumor protein p53 regulated apoptosis inducing protein 1. | 0.469 |
| TP53 | BCL2 | ENSPTRP00000014836 | ENSPTRP00000090293 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | BCL2 apoptosis regulator. | 0.998 |
| TP53 | CDKN1A | ENSPTRP00000014836 | ENSPTRP00000060292 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | 0.998 |
| TP53 | DYRK2 | ENSPTRP00000014836 | ENSPTRP00000065905 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. | 0.767 |
| TP53 | TP53AIP1 | ENSPTRP00000014836 | ENSPTRP00000007645 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Tumor protein p53 regulated apoptosis inducing protein 1. | 0.837 |
| TP53 | TP53INP1 | ENSPTRP00000014836 | ENSPTRP00000034947 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | TP53INP1 isoform 1. | 0.807 |
| TP53 | TP63 | ENSPTRP00000014836 | ENSPTRP00000027067 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.908 |
| TP53 | TP73 | ENSPTRP00000014836 | ENSPTRP00000064772 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. | 0.986 |
| TP53 | ZNF420 | ENSPTRP00000014836 | ENSPTRP00000018671 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | ZNF420 isoform 5. | 0.496 |
| TP53AIP1 | BCL2 | ENSPTRP00000007645 | ENSPTRP00000090293 | Tumor protein p53 regulated apoptosis inducing protein 1. | BCL2 apoptosis regulator. | 0.491 |
| TP53AIP1 | CDKN1A | ENSPTRP00000007645 | ENSPTRP00000060292 | Tumor protein p53 regulated apoptosis inducing protein 1. | Cyclin-dependent kinase inhibitor 1A (P21, Cip1). | 0.422 |
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