ITFG2 protein (Pan troglodytes) - STRING interaction network

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Score

ITFG2

Integrin alpha FG-GAP repeat-containing protein 2. (447 aa)

Predicted Functional Partners:

C12H12orf66

0.999

KPTN

0.999

WDR59

0.996

WDR24

0.995

NPRL2

0.995

LAMP1

0.984

CK820_G0024573

0.957

DEPDC5

0.957

DMRTC2

0.882

BMT2

0.841

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	C12H12orf66	ENSPTRP00000082851	ENSPTRP00000008794	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Chromosome 12 open reading frame 66.	0.873
BMT2	CK820_G0024573	ENSPTRP00000082851	ENSPTRP00000065815	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEPDC5 isoform 16.	0.812
BMT2	DEPDC5	ENSPTRP00000082851	ENSPTRP00000081581	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEP domain containing 5.	0.812
BMT2	DMRTC2	ENSPTRP00000082851	ENSPTRP00000092065	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DMRT like family C2.	0.422
BMT2	ITFG2	ENSPTRP00000082851	ENSPTRP00000007752	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Integrin alpha FG-GAP repeat-containing protein 2.	0.841
BMT2	KPTN	ENSPTRP00000082851	ENSPTRP00000019238	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Kaptin (Actin binding protein).	0.794
BMT2	NPRL2	ENSPTRP00000082851	ENSPTRP00000025828	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Nitrogen permease regulator-like 2.	0.807
BMT2	WDR24	ENSPTRP00000082851	ENSPTRP00000012899	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 24.	0.441
BMT2	WDR59	ENSPTRP00000082851	ENSPTRP00000014260	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 59.	0.438
C12H12orf66	BMT2	ENSPTRP00000008794	ENSPTRP00000082851	Chromosome 12 open reading frame 66.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.873
C12H12orf66	CK820_G0024573	ENSPTRP00000008794	ENSPTRP00000065815	Chromosome 12 open reading frame 66.	DEPDC5 isoform 16.	0.958
C12H12orf66	DEPDC5	ENSPTRP00000008794	ENSPTRP00000081581	Chromosome 12 open reading frame 66.	DEP domain containing 5.	0.958
C12H12orf66	ITFG2	ENSPTRP00000008794	ENSPTRP00000007752	Chromosome 12 open reading frame 66.	Integrin alpha FG-GAP repeat-containing protein 2.	0.999
C12H12orf66	KPTN	ENSPTRP00000008794	ENSPTRP00000019238	Chromosome 12 open reading frame 66.	Kaptin (Actin binding protein).	0.999
C12H12orf66	NPRL2	ENSPTRP00000008794	ENSPTRP00000025828	Chromosome 12 open reading frame 66.	Nitrogen permease regulator-like 2.	0.995
C12H12orf66	WDR24	ENSPTRP00000008794	ENSPTRP00000012899	Chromosome 12 open reading frame 66.	WD repeat domain 24.	0.996
C12H12orf66	WDR59	ENSPTRP00000008794	ENSPTRP00000014260	Chromosome 12 open reading frame 66.	WD repeat domain 59.	0.996
CK820_G0024573	BMT2	ENSPTRP00000065815	ENSPTRP00000082851	DEPDC5 isoform 16.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.812
CK820_G0024573	C12H12orf66	ENSPTRP00000065815	ENSPTRP00000008794	DEPDC5 isoform 16.	Chromosome 12 open reading frame 66.	0.958
CK820_G0024573	DEPDC5	ENSPTRP00000065815	ENSPTRP00000081581	DEPDC5 isoform 16.	DEP domain containing 5.	0.542