| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD63 | CD81 | ENSPTRP00000008613 | ENSPTRP00000074537 | Tetraspanin. | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | 0.757 |
| CD63 | CD9 | ENSPTRP00000008613 | ENSPTRP00000007803 | Tetraspanin. | Tetraspanin. | 0.860 |
| CD63 | IGSF8 | ENSPTRP00000008613 | ENSPTRP00000051684 | Tetraspanin. | Immunoglobulin superfamily member 8. | 0.446 |
| CD63 | ITGB1 | ENSPTRP00000008613 | ENSPTRP00000069754 | Tetraspanin. | Integrin beta; Belongs to the integrin beta chain family. | 0.867 |
| CD63 | TSG101 | ENSPTRP00000008613 | ENSPTRP00000062068 | Tetraspanin. | Tumor susceptibility 101. | 0.824 |
| CD81 | CD63 | ENSPTRP00000074537 | ENSPTRP00000008613 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Tetraspanin. | 0.757 |
| CD81 | CD9 | ENSPTRP00000074537 | ENSPTRP00000007803 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Tetraspanin. | 0.953 |
| CD81 | IGSF8 | ENSPTRP00000074537 | ENSPTRP00000051684 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Immunoglobulin superfamily member 8. | 0.865 |
| CD81 | ITGB1 | ENSPTRP00000074537 | ENSPTRP00000069754 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Integrin beta; Belongs to the integrin beta chain family. | 0.860 |
| CD81 | PTGFRN | ENSPTRP00000074537 | ENSPTRP00000001983 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Prostaglandin F2 receptor negative regulator. | 0.963 |
| CD81 | TSG101 | ENSPTRP00000074537 | ENSPTRP00000062068 | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | Tumor susceptibility 101. | 0.759 |
| CD9 | CD63 | ENSPTRP00000007803 | ENSPTRP00000008613 | Tetraspanin. | Tetraspanin. | 0.860 |
| CD9 | CD81 | ENSPTRP00000007803 | ENSPTRP00000074537 | Tetraspanin. | CD81 antigen; Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells. Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production. In T cells, facilitates the localization of CD247/ [...] | 0.953 |
| CD9 | IGSF8 | ENSPTRP00000007803 | ENSPTRP00000051684 | Tetraspanin. | Immunoglobulin superfamily member 8. | 0.922 |
| CD9 | ITGA3 | ENSPTRP00000007803 | ENSPTRP00000015942 | Tetraspanin. | ITGA3 isoform 6; Belongs to the integrin alpha chain family. | 0.862 |
| CD9 | ITGA6 | ENSPTRP00000007803 | ENSPTRP00000087927 | Tetraspanin. | Integrin subunit alpha 6; Belongs to the integrin alpha chain family. | 0.887 |
| CD9 | ITGB1 | ENSPTRP00000007803 | ENSPTRP00000069754 | Tetraspanin. | Integrin beta; Belongs to the integrin beta chain family. | 0.930 |
| CD9 | IZUMO3 | ENSPTRP00000007803 | ENSPTRP00000076140 | Tetraspanin. | IZUMO family member 3. | 0.896 |
| CD9 | PRKAR2A | ENSPTRP00000007803 | ENSPTRP00000091609 | Tetraspanin. | Protein kinase cAMP-dependent type II regulatory subunit alpha. | 0.850 |
| CD9 | PTGFRN | ENSPTRP00000007803 | ENSPTRP00000001983 | Tetraspanin. | Prostaglandin F2 receptor negative regulator. | 0.964 |
