STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOX5SRY (Sex determining region Y)-box 5. (765 aa)    
Predicted Functional Partners:
SOX6
SOX6 isoform 9.
  
 
 
0.807
SOX13
SRY (Sex determining region Y)-box 13.
    
 
0.723
CTNNB1
Catenin (Cadherin-associated protein), beta 1, 88kDa.
   
 0.709
SOX9
Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.
    
0.702
CEP85
Coiled-coil domain containing 21.
    
 
 0.698
FOXI2
FOXI2 isoform 1.
    
 
 0.687
TCF7
Transcription factor 7.
     
0.670
COL2A1
Collagen type II alpha 1 chain.
      
 0.642
FOXN3
FOXN3 isoform 2.
    
 
 0.638
FOXK1
FOXK1 isoform 1.
    
 
 0.585
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.