STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRASNeuroblastoma RAS viral (V-ras) oncogene homolog. (189 aa)    
Predicted Functional Partners:
BRAF
BRAF isoform 1; Belongs to the protein kinase superfamily.
   
 0.997
NF1
Neurofibromin 1.
   
 0.991
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.990
RALGDS
Ral guanine nucleotide dissociation stimulator.
   
 0.989
ARAF
V-raf murine sarcoma 3611 viral oncogene homolog.
   
 0.987
RASA1
RAS p21 protein activator (GTPase activating protein) 1.
   
 0.986
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
   
 0.986
EGFR
Receptor protein-tyrosine kinase.
   
 0.984
SHOC2
SHOC2 leucine rich repeat scaffold protein.
   
 0.980
ALK
Tyrosine-protein kinase receptor.
   
 0.977
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.