DDN protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD2AP	DDN	ENSPTRP00000084816	ENSPTRP00000008365	CD2-associated protein.	DDN isoform 1.	0.627
CD2AP	SYNPO	ENSPTRP00000084816	ENSPTRP00000047044	CD2-associated protein.	SYNPO isoform 4.	0.526
CPNE5	DDN	ENSPTRP00000030935	ENSPTRP00000008365	CPNE5 isoform 2.	DDN isoform 1.	0.588
CPNE5	KCNJ4	ENSPTRP00000030935	ENSPTRP00000073546	CPNE5 isoform 2.	Potassium voltage-gated channel subfamily J member 4.	0.555
DDN	CD2AP	ENSPTRP00000008365	ENSPTRP00000084816	DDN isoform 1.	CD2-associated protein.	0.627
DDN	CPNE5	ENSPTRP00000008365	ENSPTRP00000030935	DDN isoform 1.	CPNE5 isoform 2.	0.588
DDN	DDR1	ENSPTRP00000008365	ENSPTRP00000069688	DDN isoform 1.	Epithelial discoidin domain-containing receptor 1; Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Promotes sm [...]	0.548
DDN	KCNJ4	ENSPTRP00000008365	ENSPTRP00000073546	DDN isoform 1.	Potassium voltage-gated channel subfamily J member 4.	0.568
DDN	NCK1	ENSPTRP00000008365	ENSPTRP00000026594	DDN isoform 1.	Cytoplasmic protein.	0.649
DDN	NCK2	ENSPTRP00000008365	ENSPTRP00000021097	DDN isoform 1.	Cytoplasmic protein.	0.547
DDN	SYNGAP1	ENSPTRP00000008365	ENSPTRP00000062076	DDN isoform 1.	Synaptic Ras GTPase activating protein 1.	0.634
DDN	SYNPO	ENSPTRP00000008365	ENSPTRP00000047044	DDN isoform 1.	SYNPO isoform 4.	0.694
DDN	WWC1	ENSPTRP00000008365	ENSPTRP00000029906	DDN isoform 1.	WWC1 isoform 7.	0.693
DDN	WWC2	ENSPTRP00000008365	ENSPTRP00000093479	DDN isoform 1.	WW and C2 domain containing 2.	0.686
DDR1	DDN	ENSPTRP00000069688	ENSPTRP00000008365	Epithelial discoidin domain-containing receptor 1; Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Promotes sm [...]	DDN isoform 1.	0.548
DDR1	NCK1	ENSPTRP00000069688	ENSPTRP00000026594	Epithelial discoidin domain-containing receptor 1; Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Promotes sm [...]	Cytoplasmic protein.	0.432
DDR1	NCK2	ENSPTRP00000069688	ENSPTRP00000021097	Epithelial discoidin domain-containing receptor 1; Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Promotes sm [...]	Cytoplasmic protein.	0.674
KCNJ4	CPNE5	ENSPTRP00000073546	ENSPTRP00000030935	Potassium voltage-gated channel subfamily J member 4.	CPNE5 isoform 2.	0.555
KCNJ4	DDN	ENSPTRP00000073546	ENSPTRP00000008365	Potassium voltage-gated channel subfamily J member 4.	DDN isoform 1.	0.568
NCK1	DDN	ENSPTRP00000026594	ENSPTRP00000008365	Cytoplasmic protein.	DDN isoform 1.	0.649