STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRASPGRASP isoform 4. (394 aa)    
Predicted Functional Partners:
DLGAP3
DLG associated protein 3.
  
 
 0.770
NTRK3
NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
    
 0.709
CYTH2
CYTH2 isoform 1.
    
 
 0.690
APBA2
Amyloid beta precursor protein binding family A member 2.
    
 0.683
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
    
 0.671
GRM5
Glutamate metabotropic receptor 5.
    
 
 0.665
MAGI2
Membrane associated guanylate kinase, WW and PDZ domain containing 2.
    
 
 0.638
CYTH3
CYTH3 isoform 1.
    
 
 0.601
CYTH3-2
Cytohesin 3.
    
 
 0.601
GRM1
Glutamate receptor, metabotropic 1.
    
 
 0.598
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.