STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MFSD5Major facilitator superfamily domain containing 5. (557 aa)    
Predicted Functional Partners:
MFSD11
Major facilitator superfamily domain containing 11.
      
 0.785
C12H12orf10
Chromosome 12 open reading frame 10.
   
  
 0.759
C11H11orf49
Chromosome 11 open reading frame 49.
      
 0.719
ARHGAP1
Rho GTPase activating protein 1.
      
 0.683
ZNF408
Zinc finger protein 408.
   
  
 0.676
KPRP
KPRP isoform 1.
      
 0.656
PFDN5
Prefoldin subunit 5.
      
 0.624
PFDN5-2
Prefoldin subunit 5.
      
 0.624
MFSD3
MFSD3 isoform 1.
      
 0.599
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]
      
 0.543
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.