STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOXC8HOXC8 isoform 1. (242 aa)    
Predicted Functional Partners:
HOXC9
Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
   
 
0.865
HOXC6
HOXC6 isoform 1.
   
  
0.823
BMPR1B
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 
 0.752
SMURF1
E3 ubiquitin-protein ligase.
      
 0.736
ASXL2
ASXL transcriptional regulator 2.
    
 
 0.672
TAPT1
Transmembrane anterior posterior transformation 1.
      
 0.613
ASXL3
ASXL3 isoform 1.
    
 
 0.598
SMAD7
Mothers against decapentaplegic homolog.
   
 
 0.591
AKT1
AKT1 isoform 3; Belongs to the protein kinase superfamily.
    
 
 0.578
PBX1
Pre-B-cell leukemia homeobox 1.
    
 0.558
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.