STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB5BRAB5B, member RAS oncogene family. (227 aa)    
Predicted Functional Partners:
RAB5A
RAB5A, member RAS oncogene family.
  
 
0.987
RAB5C
T0136450 isoform 1.
  
 
0.958
RIN1
Ras and Rab interactor 1.
    
 0.957
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.955
EEA1
Early endosome antigen 1.
    
 0.940
RABGEF1
Rab5 GDP/GTP exchange factor isoform X3.
   
 0.890
ENSPTRP00000078517
annotation not available
   
 0.890
ENSPTRP00000079183
annotation not available
   
 0.890
ENSPTRP00000088204
annotation not available
   
 0.890
ENSPTRP00000087371
annotation not available
    
0.882
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.