| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACAT1 | ACLY | ENSPTRP00000007309 | ENSPTRP00000044752 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.884 |
| ACAT1 | ACO1 | ENSPTRP00000007309 | ENSPTRP00000035646 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. | 0.406 |
| ACAT1 | ACO2 | ENSPTRP00000007309 | ENSPTRP00000024853 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | ACO2 isoform 2. | 0.552 |
| ACAT1 | CS | ENSPTRP00000007309 | ENSPTRP00000008664 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Citrate synthase, mitochondrial isoform X1. | 0.947 |
| ACAT1 | DLAT | ENSPTRP00000007309 | ENSPTRP00000007349 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.929 |
| ACAT1 | FH | ENSPTRP00000007309 | ENSPTRP00000003656 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Fumarate hydratase. | 0.642 |
| ACAT1 | MDH2 | ENSPTRP00000007309 | ENSPTRP00000033039 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Malate dehydrogenase. | 0.600 |
| ACLY | ACAT1 | ENSPTRP00000044752 | ENSPTRP00000007309 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.884 |
| ACLY | ACO1 | ENSPTRP00000044752 | ENSPTRP00000035646 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. | 0.967 |
| ACLY | ACO2 | ENSPTRP00000044752 | ENSPTRP00000024853 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | ACO2 isoform 2. | 0.966 |
| ACLY | CS | ENSPTRP00000044752 | ENSPTRP00000008664 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Citrate synthase, mitochondrial isoform X1. | 0.985 |
| ACLY | DLAT | ENSPTRP00000044752 | ENSPTRP00000007349 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.982 |
| ACLY | FH | ENSPTRP00000044752 | ENSPTRP00000003656 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Fumarate hydratase. | 0.693 |
| ACLY | GOT2 | ENSPTRP00000044752 | ENSPTRP00000013976 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Aspartate aminotransferase. | 0.852 |
| ACLY | MDH1 | ENSPTRP00000044752 | ENSPTRP00000088176 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase. | 0.966 |
| ACLY | MDH2 | ENSPTRP00000044752 | ENSPTRP00000033039 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase. | 0.959 |
| ACLY | PC | ENSPTRP00000044752 | ENSPTRP00000045149 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.949 |
| ACO1 | ACAT1 | ENSPTRP00000035646 | ENSPTRP00000007309 | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.406 |
| ACO1 | ACLY | ENSPTRP00000035646 | ENSPTRP00000044752 | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.967 |
| ACO1 | ACO2 | ENSPTRP00000035646 | ENSPTRP00000024853 | Aconitase 1, soluble; Belongs to the aconitase/IPM isomerase family. | ACO2 isoform 2. | 0.937 |
