STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STAT6Signal transducer and activator of transcription. (847 aa)    
Predicted Functional Partners:
IL4R
IL4R isoform 2.
   
 0.994
JAK1
Tyrosine-protein kinase.
   
 0.991
TYK2
Tyrosine-protein kinase.
   
 0.987
NCOA1
Nuclear receptor coactivator.
    
 
 0.986
IRF9
Interferon regulatory factor 9.
   
 0.985
STAT2
Signal transducer and activator of transcription.
  
0.980
IL2RG
IL2RG isoform 1.
   
 
 0.964
CISH
Cytokine inducible SH2 containing protein.
   
 0.956
CREBBP
CREB binding protein.
    
 0.955
PTPN2
Tyrosine-protein phosphatase non-receptor type.
   
 0.952
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.