STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BEST3Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (668 aa)    
Predicted Functional Partners:
GLIPR1
GLI pathogenesis-related 1; Belongs to the CRISP family.
   
  
 0.790
ZDHHC17
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
  
 0.790
TSPAN31
TSPAN31 isoform 2; Belongs to the tetraspanin (TM4SF) family.
      
 0.790
CCT2
Chaperonin containing TCP1, subunit 2 (Beta).
      
 0.789
METTL1
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
      
 0.768
OS9
Osteosarcoma amplified 9, endoplasmic reticulum lectin.
      
 0.735
FRS2
Fibroblast growth factor receptor substrate 2.
      
 0.730
ENSPTRP00000078608
annotation not available
      
 0.728
BBS10
Bardet-Biedl syndrome 10.
      
 0.710
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
      
 0.687
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.