STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)    
Predicted Functional Partners:
RSPO1
RSPO1 isoform 3.
   
 0.998
RSPO2
R-spondin 2 homolog.
   
 0.996
RSPO3
RSPO3 isoform 1.
   
 0.983
RSPO4
RSPO4 isoform 1.
   
 0.972
LGR4
LGR4 isoform 2.
  
0.972
ZNRF3
ZNRF3 isoform 1.
    
 0.970
RNF43
Ring finger protein 43.
    
 0.968
OLFM4
OLFM4 isoform 1.
    
 
 0.691
RLN3
Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142) (By similarity).
   
 
 0.687
ADGRL1
Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.681
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.