NR2C1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NR2C1

Nuclear receptor subfamily 2, group C, member 1. (604 aa)

Predicted Functional Partners:

FKBP9

0.843

HDAC3

0.811

NRIP1

0.792

UBE2I

0.783

NCOR1

0.693

FHL2

0.636

FBXL20

0.624

NR2C2

0.624

JAZF1

0.584

BCKDHB

0.582

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCKDHB	FKBP9	ENSPTRP00000031400	ENSPTRP00000032579	BCKDHB isoform 1.	Peptidylprolyl isomerase.	0.555
BCKDHB	NR2C1	ENSPTRP00000031400	ENSPTRP00000009017	BCKDHB isoform 1.	Nuclear receptor subfamily 2, group C, member 1.	0.582
BCKDHB	UBE2I	ENSPTRP00000031400	ENSPTRP00000012969	BCKDHB isoform 1.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.441
FBXL20	FKBP9	ENSPTRP00000015488	ENSPTRP00000032579	F-box and leucine rich repeat protein 20.	Peptidylprolyl isomerase.	0.754
FBXL20	NR2C1	ENSPTRP00000015488	ENSPTRP00000009017	F-box and leucine rich repeat protein 20.	Nuclear receptor subfamily 2, group C, member 1.	0.624
FBXL20	UBE2I	ENSPTRP00000015488	ENSPTRP00000012969	F-box and leucine rich repeat protein 20.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.646
FHL2	FKBP9	ENSPTRP00000086295	ENSPTRP00000032579	FHL2 isoform 4.	Peptidylprolyl isomerase.	0.737
FHL2	NR2C1	ENSPTRP00000086295	ENSPTRP00000009017	FHL2 isoform 4.	Nuclear receptor subfamily 2, group C, member 1.	0.636
FHL2	UBE2I	ENSPTRP00000086295	ENSPTRP00000012969	FHL2 isoform 4.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.647
FKBP9	BCKDHB	ENSPTRP00000032579	ENSPTRP00000031400	Peptidylprolyl isomerase.	BCKDHB isoform 1.	0.555
FKBP9	FBXL20	ENSPTRP00000032579	ENSPTRP00000015488	Peptidylprolyl isomerase.	F-box and leucine rich repeat protein 20.	0.754
FKBP9	FHL2	ENSPTRP00000032579	ENSPTRP00000086295	Peptidylprolyl isomerase.	FHL2 isoform 4.	0.737
FKBP9	NR2C1	ENSPTRP00000032579	ENSPTRP00000009017	Peptidylprolyl isomerase.	Nuclear receptor subfamily 2, group C, member 1.	0.843
FKBP9	NR2C2	ENSPTRP00000032579	ENSPTRP00000086297	Peptidylprolyl isomerase.	NR2C2 isoform 1.	0.400
FKBP9	UBE2I	ENSPTRP00000032579	ENSPTRP00000012969	Peptidylprolyl isomerase.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.842
HDAC3	NCOR1	ENSPTRP00000029652	ENSPTRP00000075557	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor corepressor 1.	0.999
HDAC3	NR2C1	ENSPTRP00000029652	ENSPTRP00000009017	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor subfamily 2, group C, member 1.	0.811
HDAC3	NR2C2	ENSPTRP00000029652	ENSPTRP00000086297	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	NR2C2 isoform 1.	0.406
HDAC3	NRIP1	ENSPTRP00000029652	ENSPTRP00000080348	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor interacting protein 1.	0.636
HDAC3	UBE2I	ENSPTRP00000029652	ENSPTRP00000012969	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.477