NR2C1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CXXC1	NR2C1	ENSPTRP00000079629	ENSPTRP00000009017	CXXC finger protein 1.	Nuclear receptor subfamily 2, group C, member 1.	0.649
FBXL20	FKBP9	ENSPTRP00000015488	ENSPTRP00000032579	F-box and leucine rich repeat protein 20.	Peptidylprolyl isomerase.	0.787
FBXL20	NR2C1	ENSPTRP00000015488	ENSPTRP00000009017	F-box and leucine rich repeat protein 20.	Nuclear receptor subfamily 2, group C, member 1.	0.681
FBXL20	UBE2I	ENSPTRP00000015488	ENSPTRP00000012969	F-box and leucine rich repeat protein 20.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.705
FHL2	FKBP9	ENSPTRP00000086295	ENSPTRP00000032579	FHL2 isoform 4.	Peptidylprolyl isomerase.	0.802
FHL2	NR2C1	ENSPTRP00000086295	ENSPTRP00000009017	FHL2 isoform 4.	Nuclear receptor subfamily 2, group C, member 1.	0.665
FHL2	UBE2I	ENSPTRP00000086295	ENSPTRP00000012969	FHL2 isoform 4.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.675
FKBP9	FBXL20	ENSPTRP00000032579	ENSPTRP00000015488	Peptidylprolyl isomerase.	F-box and leucine rich repeat protein 20.	0.787
FKBP9	FHL2	ENSPTRP00000032579	ENSPTRP00000086295	Peptidylprolyl isomerase.	FHL2 isoform 4.	0.802
FKBP9	NR2C1	ENSPTRP00000032579	ENSPTRP00000009017	Peptidylprolyl isomerase.	Nuclear receptor subfamily 2, group C, member 1.	0.872
FKBP9	UBE2I	ENSPTRP00000032579	ENSPTRP00000012969	Peptidylprolyl isomerase.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.872
HDAC3	MED1	ENSPTRP00000029652	ENSPTRP00000015490	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.565
HDAC3	NCOR2	ENSPTRP00000029652	ENSPTRP00000088620	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor corepressor 2.	0.993
HDAC3	NR2C1	ENSPTRP00000029652	ENSPTRP00000009017	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor subfamily 2, group C, member 1.	0.837
HDAC3	NRIP1	ENSPTRP00000029652	ENSPTRP00000080348	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor interacting protein 1.	0.679
HDAC3	PML	ENSPTRP00000029652	ENSPTRP00000012429	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	PML isoform 6.	0.457
HDAC3	UBE2I	ENSPTRP00000029652	ENSPTRP00000012969	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.436
MED1	HDAC3	ENSPTRP00000015490	ENSPTRP00000029652	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.565
MED1	NCOR2	ENSPTRP00000015490	ENSPTRP00000088620	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 2.	0.681
MED1	NR2C1	ENSPTRP00000015490	ENSPTRP00000009017	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 2, group C, member 1.	0.774