NR1H4 protein (Pan troglodytes) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

NR1H4

Nuclear receptor subfamily 1 group H member 4. (486 aa)

Predicted Functional Partners:

RXRA

0.988

NCOA1

0.978

PPARGC1A

0.938

NCOR1

0.937

NCOA2

0.925

NR0B2

0.857

CYP7A1

0.848

MED1

0.842

RXRG

0.827

GPBAR1

0.824

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP7A1	GPBAR1	ENSPTRP00000034711	ENSPTRP00000059804	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	G protein-coupled bile acid receptor 1.	0.583
CYP7A1	NR0B2	ENSPTRP00000034711	ENSPTRP00000000693	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	Nuclear receptor subfamily 0 group B member 2.	0.865
CYP7A1	NR1H4	ENSPTRP00000034711	ENSPTRP00000072319	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	Nuclear receptor subfamily 1 group H member 4.	0.848
CYP7A1	PPARGC1A	ENSPTRP00000034711	ENSPTRP00000027470	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	PPARG coactivator 1 alpha.	0.460
CYP7A1	RXRA	ENSPTRP00000034711	ENSPTRP00000045122	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	Retinoid X receptor, alpha.	0.625
CYP7A1	RXRG	ENSPTRP00000034711	ENSPTRP00000081703	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	Retinoid X receptor gamma.	0.449
GPBAR1	CYP7A1	ENSPTRP00000059804	ENSPTRP00000034711	G protein-coupled bile acid receptor 1.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.583
GPBAR1	NR0B2	ENSPTRP00000059804	ENSPTRP00000000693	G protein-coupled bile acid receptor 1.	Nuclear receptor subfamily 0 group B member 2.	0.545
GPBAR1	NR1H4	ENSPTRP00000059804	ENSPTRP00000072319	G protein-coupled bile acid receptor 1.	Nuclear receptor subfamily 1 group H member 4.	0.824
MED1	NCOA1	ENSPTRP00000015490	ENSPTRP00000020127	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.800
MED1	NCOA2	ENSPTRP00000015490	ENSPTRP00000069925	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.708
MED1	NCOR1	ENSPTRP00000015490	ENSPTRP00000075557	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 1.	0.692
MED1	NR0B2	ENSPTRP00000015490	ENSPTRP00000000693	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 0 group B member 2.	0.573
MED1	NR1H4	ENSPTRP00000015490	ENSPTRP00000072319	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 1 group H member 4.	0.842
MED1	PPARGC1A	ENSPTRP00000015490	ENSPTRP00000027470	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	PPARG coactivator 1 alpha.	0.571
MED1	RXRA	ENSPTRP00000015490	ENSPTRP00000045122	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor, alpha.	0.980
MED1	RXRG	ENSPTRP00000015490	ENSPTRP00000081703	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Retinoid X receptor gamma.	0.910
NCOA1	MED1	ENSPTRP00000020127	ENSPTRP00000015490	Nuclear receptor coactivator.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.800
NCOA1	NCOA2	ENSPTRP00000020127	ENSPTRP00000069925	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.998
NCOA1	NCOR1	ENSPTRP00000020127	ENSPTRP00000075557	Nuclear receptor coactivator.	Nuclear receptor corepressor 1.	0.787