PSPC1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

PSPC1

Paraspeckle component 1. (508 aa)

Predicted Functional Partners:

NONO

0.993

SFPQ

0.990

LOC454204

0.946

RBM4

0.853

ABCF1

0.768

FUS

0.729

MATR3

0.682

CPSF6

0.567

LOC748850

0.512

HDAC1

0.512

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCF1	PSPC1	ENSPTRP00000030585	ENSPTRP00000009686	ATP-binding cassette sub-family F member 1; Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis (By similarity); Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.	Paraspeckle component 1.	0.768
CPSF6	LOC454204	ENSPTRP00000008836	ENSPTRP00000075390	CPSF6 isoform 3.	Non-POU domain-containing octamer-binding protein.	0.619
CPSF6	NONO	ENSPTRP00000008836	ENSPTRP00000037845	CPSF6 isoform 3.	non-POU domain containing octamer binding.	0.713
CPSF6	PSPC1	ENSPTRP00000008836	ENSPTRP00000009686	CPSF6 isoform 3.	Paraspeckle component 1.	0.567
CPSF6	RBM4	ENSPTRP00000008836	ENSPTRP00000006776	CPSF6 isoform 3.	RNA-binding protein 14.	0.594
CPSF6	SFPQ	ENSPTRP00000008836	ENSPTRP00000069966	CPSF6 isoform 3.	Splicing factor proline/glutamine-rich.	0.804
FUS	HDAC1	ENSPTRP00000053592	ENSPTRP00000075891	FUS isoform 7.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.449
FUS	LOC454204	ENSPTRP00000053592	ENSPTRP00000075390	FUS isoform 7.	Non-POU domain-containing octamer-binding protein.	0.676
FUS	LOC748850	ENSPTRP00000053592	ENSPTRP00000067224	FUS isoform 7.	HDAC2 isoform 9.	0.449
FUS	MATR3	ENSPTRP00000053592	ENSPTRP00000029570	FUS isoform 7.	MATR3 isoform 14.	0.735
FUS	NONO	ENSPTRP00000053592	ENSPTRP00000037845	FUS isoform 7.	non-POU domain containing octamer binding.	0.774
FUS	PSPC1	ENSPTRP00000053592	ENSPTRP00000009686	FUS isoform 7.	Paraspeckle component 1.	0.729
FUS	RBM4	ENSPTRP00000053592	ENSPTRP00000006776	FUS isoform 7.	RNA-binding protein 14.	0.657
FUS	SFPQ	ENSPTRP00000053592	ENSPTRP00000069966	FUS isoform 7.	Splicing factor proline/glutamine-rich.	0.862
HDAC1	FUS	ENSPTRP00000075891	ENSPTRP00000053592	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	FUS isoform 7.	0.449
HDAC1	LOC454204	ENSPTRP00000075891	ENSPTRP00000075390	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Non-POU domain-containing octamer-binding protein.	0.423
HDAC1	NONO	ENSPTRP00000075891	ENSPTRP00000037845	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	non-POU domain containing octamer binding.	0.501
HDAC1	PSPC1	ENSPTRP00000075891	ENSPTRP00000009686	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Paraspeckle component 1.	0.512
HDAC1	SFPQ	ENSPTRP00000075891	ENSPTRP00000069966	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Splicing factor proline/glutamine-rich.	0.713
LOC454204	CPSF6	ENSPTRP00000075390	ENSPTRP00000008836	Non-POU domain-containing octamer-binding protein.	CPSF6 isoform 3.	0.619