| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASP3 | CASP7 | ENSPTRP00000054330 | ENSPTRP00000074501 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | CASP7 isoform 1; Belongs to the peptidase C14A family. | 0.973 |
| CASP3 | CASP9 | ENSPTRP00000054330 | ENSPTRP00000089496 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | CASP9 isoform 4; Belongs to the peptidase C14A family. | 0.998 |
| CASP3 | GZMB | ENSPTRP00000054330 | ENSPTRP00000087293 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | GZMB isoform 2; Belongs to the peptidase S1 family. | 0.979 |
| CASP3 | PARP4 | ENSPTRP00000054330 | ENSPTRP00000009733 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Poly [ADP-ribose] polymerase. | 0.909 |
| CASP3 | PDE5A | ENSPTRP00000054330 | ENSPTRP00000043194 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Phosphodiesterase. | 0.405 |
| CASP3 | TEP1 | ENSPTRP00000054330 | ENSPTRP00000010340 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | Telomerase associated protein 1. | 0.463 |
| CASP7 | CASP3 | ENSPTRP00000074501 | ENSPTRP00000054330 | CASP7 isoform 1; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.973 |
| CASP7 | CASP9 | ENSPTRP00000074501 | ENSPTRP00000089496 | CASP7 isoform 1; Belongs to the peptidase C14A family. | CASP9 isoform 4; Belongs to the peptidase C14A family. | 0.987 |
| CASP7 | GZMB | ENSPTRP00000074501 | ENSPTRP00000087293 | CASP7 isoform 1; Belongs to the peptidase C14A family. | GZMB isoform 2; Belongs to the peptidase S1 family. | 0.923 |
| CASP7 | PARP4 | ENSPTRP00000074501 | ENSPTRP00000009733 | CASP7 isoform 1; Belongs to the peptidase C14A family. | Poly [ADP-ribose] polymerase. | 0.909 |
| CASP7 | TEP1 | ENSPTRP00000074501 | ENSPTRP00000010340 | CASP7 isoform 1; Belongs to the peptidase C14A family. | Telomerase associated protein 1. | 0.463 |
| CASP9 | CASP3 | ENSPTRP00000089496 | ENSPTRP00000054330 | CASP9 isoform 4; Belongs to the peptidase C14A family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.998 |
| CASP9 | CASP7 | ENSPTRP00000089496 | ENSPTRP00000074501 | CASP9 isoform 4; Belongs to the peptidase C14A family. | CASP7 isoform 1; Belongs to the peptidase C14A family. | 0.987 |
| CASP9 | PARP4 | ENSPTRP00000089496 | ENSPTRP00000009733 | CASP9 isoform 4; Belongs to the peptidase C14A family. | Poly [ADP-ribose] polymerase. | 0.909 |
| CASP9 | TEP1 | ENSPTRP00000089496 | ENSPTRP00000010340 | CASP9 isoform 4; Belongs to the peptidase C14A family. | Telomerase associated protein 1. | 0.463 |
| GZMB | CASP3 | ENSPTRP00000087293 | ENSPTRP00000054330 | GZMB isoform 2; Belongs to the peptidase S1 family. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. | 0.979 |
| GZMB | CASP7 | ENSPTRP00000087293 | ENSPTRP00000074501 | GZMB isoform 2; Belongs to the peptidase S1 family. | CASP7 isoform 1; Belongs to the peptidase C14A family. | 0.923 |
| GZMB | PARP4 | ENSPTRP00000087293 | ENSPTRP00000009733 | GZMB isoform 2; Belongs to the peptidase S1 family. | Poly [ADP-ribose] polymerase. | 0.904 |
| MVP | PARP14 | ENSPTRP00000040670 | ENSPTRP00000026370 | Major vault protein. | Poly [ADP-ribose] polymerase. | 0.532 |
| MVP | PARP4 | ENSPTRP00000040670 | ENSPTRP00000009733 | Major vault protein. | Poly [ADP-ribose] polymerase. | 0.974 |
