| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LTBR | MAP3K14 | ENSPTRP00000007817 | ENSPTRP00000056654 | Lymphotoxin beta receptor (TNFR superfamily, member 3). | Mitogen-activated protein kinase kinase kinase 14. | 0.967 |
| LTBR | TNF | ENSPTRP00000007817 | ENSPTRP00000069905 | Lymphotoxin beta receptor (TNFR superfamily, member 3). | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.731 |
| LTBR | TNFRSF11A | ENSPTRP00000007817 | ENSPTRP00000089437 | Lymphotoxin beta receptor (TNFR superfamily, member 3). | TNF receptor superfamily member 11a. | 0.580 |
| LTBR | TNFSF11 | ENSPTRP00000007817 | ENSPTRP00000009919 | Lymphotoxin beta receptor (TNFR superfamily, member 3). | Tumor necrosis factor ligand superfamily member. | 0.750 |
| LTBR | TNFSF12 | ENSPTRP00000007817 | ENSPTRP00000014818 | Lymphotoxin beta receptor (TNFR superfamily, member 3). | Tumor necrosis factor (Ligand) superfamily, member 12; Belongs to the tumor necrosis factor family. | 0.619 |
| LTBR | TNFSF13B | ENSPTRP00000007817 | ENSPTRP00000010240 | Lymphotoxin beta receptor (TNFR superfamily, member 3). | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. | 0.736 |
| MAP3K14 | LTBR | ENSPTRP00000056654 | ENSPTRP00000007817 | Mitogen-activated protein kinase kinase kinase 14. | Lymphotoxin beta receptor (TNFR superfamily, member 3). | 0.967 |
| MAP3K14 | TNF | ENSPTRP00000056654 | ENSPTRP00000069905 | Mitogen-activated protein kinase kinase kinase 14. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.533 |
| MAP3K14 | TNFRSF11A | ENSPTRP00000056654 | ENSPTRP00000089437 | Mitogen-activated protein kinase kinase kinase 14. | TNF receptor superfamily member 11a. | 0.584 |
| MAP3K14 | TNFSF11 | ENSPTRP00000056654 | ENSPTRP00000009919 | Mitogen-activated protein kinase kinase kinase 14. | Tumor necrosis factor ligand superfamily member. | 0.787 |
| MAP3K14 | TNFSF12 | ENSPTRP00000056654 | ENSPTRP00000014818 | Mitogen-activated protein kinase kinase kinase 14. | Tumor necrosis factor (Ligand) superfamily, member 12; Belongs to the tumor necrosis factor family. | 0.600 |
| MAP3K14 | TNFSF13B | ENSPTRP00000056654 | ENSPTRP00000010240 | Mitogen-activated protein kinase kinase kinase 14. | Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family. | 0.733 |
| MITF | TNFSF11 | ENSPTRP00000085305 | ENSPTRP00000009919 | MITF isoform 1. | Tumor necrosis factor ligand superfamily member. | 0.875 |
| SLC13A2 | TNFSF11 | ENSPTRP00000015222 | ENSPTRP00000009919 | Solute carrier family 13 member 2. | Tumor necrosis factor ligand superfamily member. | 0.804 |
| TNF | LTBR | ENSPTRP00000069905 | ENSPTRP00000007817 | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | Lymphotoxin beta receptor (TNFR superfamily, member 3). | 0.731 |
| TNF | MAP3K14 | ENSPTRP00000069905 | ENSPTRP00000056654 | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | Mitogen-activated protein kinase kinase kinase 14. | 0.533 |
| TNF | TNFRSF11A | ENSPTRP00000069905 | ENSPTRP00000089437 | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | TNF receptor superfamily member 11a. | 0.592 |
| TNF | TNFRSF11B | ENSPTRP00000069905 | ENSPTRP00000035110 | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. | 0.710 |
| TNF | TNFSF11 | ENSPTRP00000069905 | ENSPTRP00000009919 | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | Tumor necrosis factor ligand superfamily member. | 0.799 |
| TNF | TNFSF12 | ENSPTRP00000069905 | ENSPTRP00000014818 | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | Tumor necrosis factor (Ligand) superfamily, member 12; Belongs to the tumor necrosis factor family. | 0.773 |
