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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)    
Predicted Functional Partners:
ADH5
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.995
ENSPTRP00000063234
annotation not available
 0.959
ENSPTRP00000090441
annotation not available
 
 0.950
ADH6
Alcohol dehydrogenase 6 (class V).
 0.925
ADH7
ADH7 isoform 5.
 0.925
ADH4
Alcohol dehydrogenase 4 (class II), pi polypeptide.
 0.921
ADH1A
Alcohol dehydrogenase 1A (class I), alpha polypeptide.
 0.919
ADH1B
All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal.
 0.919
SORD
Sorbitol dehydrogenase.
  
 
 0.881
ENSPTRP00000069545
annotation not available
  
 
 0.881
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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