| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADH1A | ADH1B | ENSPTRP00000028008 | ENSPTRP00000071388 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | 0.973 |
| ADH1A | ADH6 | ENSPTRP00000028008 | ENSPTRP00000028007 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | Alcohol dehydrogenase 6 (class V). | 0.450 |
| ADH1A | ESD | ENSPTRP00000028008 | ENSPTRP00000009965 | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.919 |
| ADH1B | ADH1A | ENSPTRP00000071388 | ENSPTRP00000028008 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | 0.973 |
| ADH1B | ADH6 | ENSPTRP00000071388 | ENSPTRP00000028007 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | Alcohol dehydrogenase 6 (class V). | 0.466 |
| ADH1B | ESD | ENSPTRP00000071388 | ENSPTRP00000009965 | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.919 |
| ADH4 | ADH6 | ENSPTRP00000069873 | ENSPTRP00000028007 | Alcohol dehydrogenase 4 (class II), pi polypeptide. | Alcohol dehydrogenase 6 (class V). | 0.511 |
| ADH4 | ESD | ENSPTRP00000069873 | ENSPTRP00000009965 | Alcohol dehydrogenase 4 (class II), pi polypeptide. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.921 |
| ADH5 | ESD | ENSPTRP00000028003 | ENSPTRP00000009965 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.995 |
| ADH6 | ADH1A | ENSPTRP00000028007 | ENSPTRP00000028008 | Alcohol dehydrogenase 6 (class V). | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | 0.450 |
| ADH6 | ADH1B | ENSPTRP00000028007 | ENSPTRP00000071388 | Alcohol dehydrogenase 6 (class V). | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | 0.466 |
| ADH6 | ADH4 | ENSPTRP00000028007 | ENSPTRP00000069873 | Alcohol dehydrogenase 6 (class V). | Alcohol dehydrogenase 4 (class II), pi polypeptide. | 0.511 |
| ADH6 | ESD | ENSPTRP00000028007 | ENSPTRP00000009965 | Alcohol dehydrogenase 6 (class V). | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.925 |
| ADH7 | ESD | ENSPTRP00000063830 | ENSPTRP00000009965 | ADH7 isoform 5. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.925 |
| ENSPTRP00000063234 | ESD | ENSPTRP00000063234 | ENSPTRP00000009965 | annotation not available | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.959 |
| ENSPTRP00000069545 | ESD | ENSPTRP00000069545 | ENSPTRP00000009965 | annotation not available | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.881 |
| ENSPTRP00000090441 | ESD | ENSPTRP00000090441 | ENSPTRP00000009965 | annotation not available | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.950 |
| ESD | ADH1A | ENSPTRP00000009965 | ENSPTRP00000028008 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | Alcohol dehydrogenase 1A (class I), alpha polypeptide. | 0.919 |
| ESD | ADH1B | ENSPTRP00000009965 | ENSPTRP00000071388 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate to retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. | 0.919 |
| ESD | ADH4 | ENSPTRP00000009965 | ENSPTRP00000069873 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | Alcohol dehydrogenase 4 (class II), pi polypeptide. | 0.921 |