| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DLAT | DLD | ENSPTRP00000007349 | ENSPTRP00000086612 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyl dehydrogenase. | 0.999 |
| DLAT | DLST | ENSPTRP00000007349 | ENSPTRP00000011110 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). | 0.939 |
| DLAT | MMUT | ENSPTRP00000007349 | ENSPTRP00000031193 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Methylmalonyl CoA mutase. | 0.819 |
| DLAT | SDHA | ENSPTRP00000007349 | ENSPTRP00000048366 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.599 |
| DLAT | SDHB | ENSPTRP00000007349 | ENSPTRP00000000434 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.766 |
| DLAT | SUCLA2 | ENSPTRP00000007349 | ENSPTRP00000009968 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.949 |
| DLAT | SUCLG1 | ENSPTRP00000007349 | ENSPTRP00000020798 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.974 |
| DLAT | SUCLG2 | ENSPTRP00000007349 | ENSPTRP00000079150 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.946 |
| DLD | DLAT | ENSPTRP00000086612 | ENSPTRP00000007349 | Dihydrolipoyl dehydrogenase. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
| DLD | DLST | ENSPTRP00000086612 | ENSPTRP00000011110 | Dihydrolipoyl dehydrogenase. | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). | 0.999 |
| DLD | SDHA | ENSPTRP00000086612 | ENSPTRP00000048366 | Dihydrolipoyl dehydrogenase. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.773 |
| DLD | SDHB | ENSPTRP00000086612 | ENSPTRP00000000434 | Dihydrolipoyl dehydrogenase. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.818 |
| DLD | SUCLA2 | ENSPTRP00000086612 | ENSPTRP00000009968 | Dihydrolipoyl dehydrogenase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.957 |
| DLD | SUCLG1 | ENSPTRP00000086612 | ENSPTRP00000020798 | Dihydrolipoyl dehydrogenase. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.932 |
| DLD | SUCLG2 | ENSPTRP00000086612 | ENSPTRP00000079150 | Dihydrolipoyl dehydrogenase. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.826 |
| DLST | DLAT | ENSPTRP00000011110 | ENSPTRP00000007349 | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.939 |
| DLST | DLD | ENSPTRP00000011110 | ENSPTRP00000086612 | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). | Dihydrolipoyl dehydrogenase. | 0.999 |
| DLST | MMUT | ENSPTRP00000011110 | ENSPTRP00000031193 | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). | Methylmalonyl CoA mutase. | 0.812 |
| DLST | SDHA | ENSPTRP00000011110 | ENSPTRP00000048366 | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.605 |
| DLST | SDHB | ENSPTRP00000011110 | ENSPTRP00000000434 | Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex). | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.816 |
