STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPC6GPC6 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa)    
Predicted Functional Partners:
GPC4
GPC4 isoform 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
  
 
0.825
PCOLCE2
Procollagen C-endopeptidase enhancer 2.
      
 0.705
PRDM5
Zinc finger protein.
      
 0.647
HS3ST4
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.623
NDST1
N-deacetylase/N-sulfotransferase (Heparan glucosaminyl) 1.
    
 0.600
NOTUM
Notum, palmitoleoyl-protein carboxylesterase.
    
 0.600
GPC5
GPC5 isoform 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
0.596
HS3ST5
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.589
SDC2
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.577
EXT1
Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family.
     
 0.570
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.