STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFNB2EFNB2 isoform 1; Belongs to the ephrin family. (333 aa)    
Predicted Functional Partners:
EPHB2
EPH receptor B2.
   
 0.998
EPHB4
EPH receptor B4.
   
 0.997
EPHB1
EPH receptor B1.
   
 0.997
EPHB3
EPHB3 isoform 1.
   
 0.994
EPHA4
EPH receptor A4.
   
 0.992
EPHB6
Ephrin type-B receptor 6; Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).
   
 0.991
NCK2
Cytoplasmic protein.
    
 0.987
EPHB4-2
EPH receptor B4.
   
 0.974
EFNB3
EFNB3 isoform 1; Belongs to the ephrin family.
    
0.952
EFNB1
EFNB1 isoform 1; Belongs to the ephrin family.
    
0.952
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.