PROZ protein (Pan troglodytes) - STRING interaction network

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Predicted Interactions

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Score

PROZ

Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (422 aa)

Predicted Functional Partners:

SERPINA10

0.962

SERPINC1

0.701

F2

0.650

F3

0.631

F5

0.624

GGCX

0.613

FGG

0.578

F13B

0.576

FURIN

0.568

F8

0.541

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F13B	F2	ENSPTRP00000003013	ENSPTRP00000006168	Coagulation factor XIII B chain.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.974
F13B	F5	ENSPTRP00000003013	ENSPTRP00000039644	Coagulation factor XIII B chain.	F5 isoform 2; Belongs to the multicopper oxidase family.	0.553
F13B	F8	ENSPTRP00000003013	ENSPTRP00000042755	Coagulation factor XIII B chain.	Coagulation factor VIII; Belongs to the multicopper oxidase family.	0.542
F13B	FGG	ENSPTRP00000003013	ENSPTRP00000083481	Coagulation factor XIII B chain.	Fibrinogen gamma chain.	0.814
F13B	PROZ	ENSPTRP00000003013	ENSPTRP00000010287	Coagulation factor XIII B chain.	Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family.	0.576
F13B	SERPINA10	ENSPTRP00000003013	ENSPTRP00000011382	Coagulation factor XIII B chain.	SERPINA10 isoform 2; Belongs to the serpin family.	0.498
F13B	SERPINC1	ENSPTRP00000003013	ENSPTRP00000002829	Coagulation factor XIII B chain.	Serpin family C member 1; Belongs to the serpin family.	0.699
F2	F13B	ENSPTRP00000006168	ENSPTRP00000003013	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor XIII B chain.	0.974
F2	F3	ENSPTRP00000006168	ENSPTRP00000040007	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	0.919
F2	F5	ENSPTRP00000006168	ENSPTRP00000039644	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	F5 isoform 2; Belongs to the multicopper oxidase family.	0.997
F2	F8	ENSPTRP00000006168	ENSPTRP00000042755	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VIII; Belongs to the multicopper oxidase family.	0.934
F2	FGG	ENSPTRP00000006168	ENSPTRP00000083481	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Fibrinogen gamma chain.	0.999
F2	FURIN	ENSPTRP00000006168	ENSPTRP00000012755	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Furin (Paired basic amino acid cleaving enzyme); Belongs to the peptidase S8 family.	0.682
F2	GGCX	ENSPTRP00000006168	ENSPTRP00000020816	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Gamma-glutamyl carboxylase.	0.867
F2	PROZ	ENSPTRP00000006168	ENSPTRP00000010287	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family.	0.650
F2	SERPINA10	ENSPTRP00000006168	ENSPTRP00000011382	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	SERPINA10 isoform 2; Belongs to the serpin family.	0.711
F2	SERPINC1	ENSPTRP00000006168	ENSPTRP00000002829	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family C member 1; Belongs to the serpin family.	0.999
F3	F2	ENSPTRP00000040007	ENSPTRP00000006168	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.919
F3	F5	ENSPTRP00000040007	ENSPTRP00000039644	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	F5 isoform 2; Belongs to the multicopper oxidase family.	0.461
F3	F8	ENSPTRP00000040007	ENSPTRP00000042755	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Coagulation factor VIII; Belongs to the multicopper oxidase family.	0.674