STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL4ACUL4A isoform 5; Belongs to the cullin family. (759 aa)    
Predicted Functional Partners:
DCAF1
Vpr (HIV-1) binding protein.
   
 0.999
DDB1
Damage-specific DNA binding protein 1, 127kDa.
   
 0.999
RBX1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.994
CUL4B
CUL4B isoform 3; Belongs to the cullin family.
  
 
0.991
DDB2
Damage-specific DNA binding protein 2, 48kDa.
    
 0.976
ERCC8
Excision repair cross-complementing rodent repair deficiency, complementation group 8.
    
 0.968
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.962
DCAF11
T0103467 isoform 1.
    
 0.958
NEDD8
Ubiquitin-like protein Nedd8.
    
 0.950
CRBN
CRBN isoform 1.
    
 
 0.949
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.