OSGEP protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPTRP00000059911	LAGE3	ENSPTRP00000059911	ENSPTRP00000042271	annotation not available	L antigen family, member 3.	0.901
ENSPTRP00000059911	OSGEP	ENSPTRP00000059911	ENSPTRP00000010343	annotation not available	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.900
ENSPTRP00000059911	TP53RK	ENSPTRP00000059911	ENSPTRP00000063082	annotation not available	TP53 regulating kinase.	0.900
GON7	OSGEP	ENSPTRP00000073896	ENSPTRP00000010343	Chromosome 14 open reading frame 142.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.985
GON7	TP53RK	ENSPTRP00000073896	ENSPTRP00000063082	Chromosome 14 open reading frame 142.	TP53 regulating kinase.	0.985
GON7	TPRKB	ENSPTRP00000073896	ENSPTRP00000020705	Chromosome 14 open reading frame 142.	TP53RK binding protein; Belongs to the CGI121/TPRKB family.	0.901
GON7	YRDC	ENSPTRP00000073896	ENSPTRP00000081010	Chromosome 14 open reading frame 142.	YRDC isoform 1.	0.495
HYKK	OSGEP	ENSPTRP00000045540	ENSPTRP00000010343	HYKK isoform 3.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.791
LAGE3	ENSPTRP00000059911	ENSPTRP00000042271	ENSPTRP00000059911	L antigen family, member 3.	annotation not available	0.901
LAGE3	OSGEP	ENSPTRP00000042271	ENSPTRP00000010343	L antigen family, member 3.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.900
LAGE3	TP53RK	ENSPTRP00000042271	ENSPTRP00000063082	L antigen family, member 3.	TP53 regulating kinase.	0.900
NUP43	OSGEP	ENSPTRP00000071735	ENSPTRP00000010343	Nucleoporin 43kDa.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.831
NUP43	TP53RK	ENSPTRP00000071735	ENSPTRP00000063082	Nucleoporin 43kDa.	TP53 regulating kinase.	0.910
NUP43	TPRKB	ENSPTRP00000071735	ENSPTRP00000020705	Nucleoporin 43kDa.	TP53RK binding protein; Belongs to the CGI121/TPRKB family.	0.910
OSGEP	ENSPTRP00000059911	ENSPTRP00000010343	ENSPTRP00000059911	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	annotation not available	0.900
OSGEP	GON7	ENSPTRP00000010343	ENSPTRP00000073896	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Chromosome 14 open reading frame 142.	0.985
OSGEP	HYKK	ENSPTRP00000010343	ENSPTRP00000045540	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	HYKK isoform 3.	0.791
OSGEP	LAGE3	ENSPTRP00000010343	ENSPTRP00000042271	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	L antigen family, member 3.	0.900
OSGEP	NUP43	ENSPTRP00000010343	ENSPTRP00000071735	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Nucleoporin 43kDa.	0.831
OSGEP	SLC4A1AP	ENSPTRP00000010343	ENSPTRP00000020230	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Solute carrier family 4 (Anion exchanger), member 1, adaptor protein.	0.730