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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)    
Predicted Functional Partners:
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha.
     
 0.930
MTMR4
Myotubularin related protein 4.
     
 0.918
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase, type II, beta.
     
 0.917
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma.
     
 0.917
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
     
 0.911
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
     
  0.909
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
     
 0.909
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
     
  0.909
MTM1
MTM1 isoform 1.
     
 0.906
OCRL
OCRL inositol polyphosphate-5-phosphatase.
     
 0.905
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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