PCK2 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	ENO1	ENSPTRP00000044752	ENSPTRP00000000207	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	ENO1 isoform 2.	0.742
ACLY	ENO2	ENSPTRP00000044752	ENSPTRP00000065761	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Enolase 2 (Gamma, neuronal).	0.548
ACLY	ENO3	ENSPTRP00000044752	ENSPTRP00000014708	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Enolase 3 (Beta, muscle).	0.581
ACLY	LOC457842	ENSPTRP00000044752	ENSPTRP00000076251	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Alpha-enolase pseudogene.	0.571
ACLY	MDH1	ENSPTRP00000044752	ENSPTRP00000088176	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malate dehydrogenase.	0.966
ACLY	MDH2	ENSPTRP00000044752	ENSPTRP00000033039	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Malate dehydrogenase.	0.959
ACLY	PC	ENSPTRP00000044752	ENSPTRP00000045149	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.949
ACLY	PCK1	ENSPTRP00000044752	ENSPTRP00000023500	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Phosphoenolpyruvate carboxykinase 1.	0.927
ACLY	PCK2	ENSPTRP00000044752	ENSPTRP00000010507	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Phosphoenolpyruvate carboxykinase 2, mitochondrial.	0.941
ENO1	ACLY	ENSPTRP00000000207	ENSPTRP00000044752	ENO1 isoform 2.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.742
ENO1	ENO2	ENSPTRP00000000207	ENSPTRP00000065761	ENO1 isoform 2.	Enolase 2 (Gamma, neuronal).	0.978
ENO1	ENO3	ENSPTRP00000000207	ENSPTRP00000014708	ENO1 isoform 2.	Enolase 3 (Beta, muscle).	0.997
ENO1	ENO4	ENSPTRP00000000207	ENSPTRP00000080724	ENO1 isoform 2.	ENO4 isoform 3.	0.961
ENO1	LOC457842	ENSPTRP00000000207	ENSPTRP00000076251	ENO1 isoform 2.	Alpha-enolase pseudogene.	0.900
ENO1	MDH1	ENSPTRP00000000207	ENSPTRP00000088176	ENO1 isoform 2.	Malate dehydrogenase.	0.624
ENO1	MDH2	ENSPTRP00000000207	ENSPTRP00000033039	ENO1 isoform 2.	Malate dehydrogenase.	0.494
ENO1	PCK1	ENSPTRP00000000207	ENSPTRP00000023500	ENO1 isoform 2.	Phosphoenolpyruvate carboxykinase 1.	0.954
ENO1	PCK2	ENSPTRP00000000207	ENSPTRP00000010507	ENO1 isoform 2.	Phosphoenolpyruvate carboxykinase 2, mitochondrial.	0.959
ENO2	ACLY	ENSPTRP00000065761	ENSPTRP00000044752	Enolase 2 (Gamma, neuronal).	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.548
ENO2	ENO1	ENSPTRP00000065761	ENSPTRP00000000207	Enolase 2 (Gamma, neuronal).	ENO1 isoform 2.	0.978