STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP4K5Mitogen-activated protein kinase kinase kinase kinase 5; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (846 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
   
 
 0.856
CRK
V-crk sarcoma virus CT10 oncogene homolog (Avian).
    
 
 0.833
PRDX3
PRDX3 isoform 1.
    
 
 0.689
CLPX
ClpX caseinolytic peptidase X homolog.
      
 0.653
UBA1
UBA1 isoform 3; Belongs to the ubiquitin-activating E1 family.
   
  
 0.648
POC1B
POC1 centriolar protein homolog B isoform X2.
   
  
 0.631
PDIA6
PDIA6 isoform 2; Belongs to the protein disulfide isomerase family.
    
 
 0.628
TAF1D
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa.
      
 0.623
OLIG3
Oligodendrocyte transcription factor 3.
      
 0.608
UFL1
UFM1 specific ligase 1.
      
 0.604
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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