STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTX2Orthodenticle homeobox 2. (297 aa)    
Predicted Functional Partners:
SIX3
SIX homeobox 3.
   
 
 0.741
FOXA2
FOXA2 isoform 1.
   
 
 0.736
SIX6
SIX homeobox 6.
   
 
 0.695
SOX2
SRY-box transcription factor 2.
   
 
 0.695
SOX1
SOX1 isoform 1.
   
 
 0.666
LMX1A
LIM homeobox transcription factor 1 alpha.
    
 
 0.647
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 
 0.647
PAX2
PAX2 isoform 1.
   
  
 0.628
RCVRN
RCVRN isoform 1.
   
  
 0.622
SOX3
SRY-box transcription factor 3.
   
 
 0.600
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.