| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARAF | BRAF | ENSPTRP00000083580 | ENSPTRP00000079485 | V-raf murine sarcoma 3611 viral oncogene homolog. | BRAF isoform 1; Belongs to the protein kinase superfamily. | 0.993 |
| ARAF | PRKCH | ENSPTRP00000083580 | ENSPTRP00000010886 | V-raf murine sarcoma 3611 viral oncogene homolog. | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | 0.915 |
| BRAF | ARAF | ENSPTRP00000079485 | ENSPTRP00000083580 | BRAF isoform 1; Belongs to the protein kinase superfamily. | V-raf murine sarcoma 3611 viral oncogene homolog. | 0.993 |
| BRAF | PRKCH | ENSPTRP00000079485 | ENSPTRP00000010886 | BRAF isoform 1; Belongs to the protein kinase superfamily. | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | 0.921 |
| CARD11 | PDPK1 | ENSPTRP00000085421 | ENSPTRP00000090334 | Caspase recruitment domain family, member 11. | 3-phosphoinositide dependent protein kinase-1. | 0.650 |
| CARD11 | PRKCH | ENSPTRP00000085421 | ENSPTRP00000010886 | Caspase recruitment domain family, member 11. | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | 0.641 |
| CARD11 | RBCK1 | ENSPTRP00000085421 | ENSPTRP00000022503 | Caspase recruitment domain family, member 11. | RANBP2-type and C3HC4-type zinc finger containing 1. | 0.435 |
| KLHL8 | PRKCH | ENSPTRP00000027924 | ENSPTRP00000010886 | Kelch like family member 8. | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | 0.738 |
| KLHL8 | PSORS1C1 | ENSPTRP00000027924 | ENSPTRP00000058415 | Kelch like family member 8. | Psoriasis susceptibility 1 candidate gene 1 protein homolog. | 0.856 |
| PDPK1 | CARD11 | ENSPTRP00000090334 | ENSPTRP00000085421 | 3-phosphoinositide dependent protein kinase-1. | Caspase recruitment domain family, member 11. | 0.650 |
| PDPK1 | PRKCH | ENSPTRP00000090334 | ENSPTRP00000010886 | 3-phosphoinositide dependent protein kinase-1. | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | 0.720 |
| PDPK1 | RHOA | ENSPTRP00000090334 | ENSPTRP00000025759 | 3-phosphoinositide dependent protein kinase-1. | Ras homolog family member A. | 0.521 |
| PDPK1 | RND1 | ENSPTRP00000090334 | ENSPTRP00000008358 | 3-phosphoinositide dependent protein kinase-1. | RND1 isoform 1. | 0.521 |
| PRKCH | ARAF | ENSPTRP00000010886 | ENSPTRP00000083580 | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | V-raf murine sarcoma 3611 viral oncogene homolog. | 0.915 |
| PRKCH | BRAF | ENSPTRP00000010886 | ENSPTRP00000079485 | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | BRAF isoform 1; Belongs to the protein kinase superfamily. | 0.921 |
| PRKCH | CARD11 | ENSPTRP00000010886 | ENSPTRP00000085421 | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | Caspase recruitment domain family, member 11. | 0.641 |
| PRKCH | KLHL8 | ENSPTRP00000010886 | ENSPTRP00000027924 | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | Kelch like family member 8. | 0.738 |
| PRKCH | PDPK1 | ENSPTRP00000010886 | ENSPTRP00000090334 | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | 3-phosphoinositide dependent protein kinase-1. | 0.720 |
| PRKCH | PSORS1C1 | ENSPTRP00000010886 | ENSPTRP00000058415 | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | Psoriasis susceptibility 1 candidate gene 1 protein homolog. | 0.653 |
| PRKCH | RBCK1 | ENSPTRP00000010886 | ENSPTRP00000022503 | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] | RANBP2-type and C3HC4-type zinc finger containing 1. | 0.579 |