STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)    
Predicted Functional Partners:
EP300
E1A binding protein p300.
    
 0.999
ARNT
Aryl hydrocarbon receptor nuclear translocator.
   
0.999
CREBBP
CREB binding protein.
    
 0.999
VHL
Von Hippel-Lindau tumor suppressor.
    
 0.999
EGLN1
EGLN1 isoform 1.
    
 0.998
HIF1AN
Hypoxia inducible factor 1, alpha subunit inhibitor.
    
 0.997
EPAS1
Endothelial PAS domain protein 1.
   
0.997
ARNT2
ARNT2 isoform 2.
   
0.996
EGLN2
T0107007 isoform 1.
    
 0.994
LOC744141
Elongin-C-like.
    
 0.993
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.