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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZFYVE26Zinc finger, FYVE domain containing 26. (2513 aa)    
Predicted Functional Partners:
SPG11
SPG11 isoform 4.
   
 
 0.875
AP5Z1
Adaptor related protein complex 5 subunit zeta 1.
      
 0.828
TXLNB
TXLNB isoform 1.
      
 0.783
TMEM236
Transmembrane protein 236.
      
 0.773
IGSF5
LOW QUALITY PROTEIN: immunoglobulin superfamily member 5.
      
 0.724
PRPF6
PRP6 pre-mRNA processing factor 6 homolog.
      
 0.723
AP5S1
Adaptor related protein complex 5 subunit sigma 1.
    
 
 0.711
AP5B1
Adaptor related protein complex 5 subunit beta 1.
      
 0.675
EIF1AX
Eukaryotic translation initiation factor 1A X-linked.
      
 0.673
TTC19
TTC19 isoform 2.
      
 0.667
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.